ECI Vaccine IX 2024 -- Self-amplifying RNA (sa mRNA) formulated in lipid nanoparticles (LNPs) is a novel vaccine modality and is being used to develop a Marburg Virus vaccine comprising the Glycoprotein (MARV) sa mRNA. Imidazoquinoline TLR-7 agonists have been encapsulated with the MARV sa mRNA-LNP with the aim of testing for adjuvancy in vivo.

ECI Vaccine IX 2024 -- Self-amplifying RNA (sa mRNA) formulated in lipid nanoparticles (LNPs) is a novel vaccine modality and is being used to develop a Marburg Virus vaccine comprising the Glycoprotein (MARV) sa mRNA.

ECI Vaccine IX 2024 -- Self-amplifying RNA (sa mRNA) formulated in lipid nanoparticles (LNPs) is a novel vaccine modality and is being used to develop a Marburg Virus vaccine comprising the Glycoprotein (MARV) sa mRNA.

OBN & University of Reading Pain Research and Therapeutics Conference 2024 -- Drug abuse liability assessment is required for drugs (parent or major metabolite) that penetrate the brain, regardless of the therapeutic indication.

ASMS 2024 -- According to Verified Market Research, at-home microsampling blood collection market size was valued at USD 8.9 billion in 2021 and is projected to reach USD 13.2 billion by 2027, growing at a CAGR of 5.1% from 2022 to 2030 (Jersey City, NJ, Aug. 17, 2022).

ESTIV Congress 2024 -- Tumour formation is a multi-stage process including an initiation stage (genomic level) and a promotion stage (cellular level). If required for regulatory submissions, the gold-standard method assay for carcinogenicity potential is the 2-year rodent carcinogenicity assay.

ALL is more commonly found in young children but also arises in older adults. Children have a >80% cure rate while adults only have a 20-30% cure rate. A similar disease is chronic lymphocytic leukemia (CLL) which is generally diagnosed in older adults.

Even though a number of advances have been made in cancer treatments and surgical approaches, little progress in ovarian cancer therapy has provided a meaningful impact on this patient population.

Researchers use preclinical mouse modeling of lymphoma to explore novel combination strategies of conventional chemotherapy or radiation and immunomodulatory agents.

Contact the preclinical oncology scientific team to learn more.