Test Details
Methodology
Polymerase chain reaction (PCR) amplification and viral culture. PhenoSense® is a trademark of Monogram Biosciences®.
Result Turnaround Time
16 - 22 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Determines viral phenotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), non-nucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI). Viral replication capacity is also included.
Limitations
This procedure should be used for patients with documented HIV-1 infection and viral loads ≥500 copies/mL.
References
Specimen Requirements
Specimen
Plasma, frozen
Volume
3 mL
Container
Lavender-top (EDTA) or plasma preparation tube (PPT™)
Collection Instructions
Collect specimen in two lavender-top (EDTA) tubes or two PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more polypropylene screw-capped tube(s) (not "pop-top" tube or "snap-cap"), and freeze. Ship specimen frozen. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze
Causes for Rejection
PPT™ not centrifuged; quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen; specimen exposed to repeated freeze/thaw cycles; specimen received in “pop-top” or “snap-cap” tube
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 551800 | PhenoSense(R) | 551503 | PhenoSense(R) PDF | 45182-3 | ||
| 551800 | PhenoSense(R) | 551801 | PhenoSense(R) | 49665-3 | ||
| 551800 | PhenoSense(R) | 551504 | PhenoSense(R) Interpretation | 48767-8 | ||
| Order Code | 551800 | |||||
| Order Code Name | PhenoSense(R) | |||||
| Order Loinc | ||||||
| Result Code | 551503 | |||||
| Result Code Name | PhenoSense(R) PDF | |||||
| UofM | ||||||
| Result LOINC | 45182-3 | |||||
| Order Code | 551800 | |||||
| Order Code Name | PhenoSense(R) | |||||
| Order Loinc | ||||||
| Result Code | 551801 | |||||
| Result Code Name | PhenoSense(R) | |||||
| UofM | ||||||
| Result LOINC | 49665-3 | |||||
| Order Code | 551800 | |||||
| Order Code Name | PhenoSense(R) | |||||
| Order Loinc | ||||||
| Result Code | 551504 | |||||
| Result Code Name | PhenoSense(R) Interpretation | |||||
| UofM | ||||||
| Result LOINC | 48767-8 |