March 4, 2025

Continuous intravenous infusion in mice to support drug development: An update to include juvenile testing

IAT Congress 2025 -- To support development of compounds requiring a constant exposure level, toxicology studies can be conducted with a continuous intravenous infusion method of administration, using surgically prepared animals, for up to 24 hours a day. Until recently, the rat has been the species of choice for such testing, but an alternative species can be the mouse and, therefore, a mouse vascular infusion model was developed for repeated dosing/long-term toxicity infusion studies. Typically, this would involve adult animals; however, based on a requirement to support use of drugs in the paediatric population, there is a potential need to dose animals of juvenile age. This poster will present results showing how vascular continuous infusion in mice with tail-cuff exteriorization has been developed and refined, along with the successful use of two other infusion models in juvenile-age mice (tail cuff and vascular access button exteriorisation). 
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March 4, 2025

Inhalation rat tube restraint – Best practice guidance

IAT Congress 2025 -- To facilitate the administration of test article via the inhalation route with rats, the tube restraint provides a safe and practical solution. However, incorrect loading and restraint within the tube can cause injury, discomfort and stress to the animal. To ensure this is prevented, training in this procedure has been developed to ensure awareness and correct performance of the technique. It also enables greater understanding of issues that can occur. 
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<span>Seven tips to reduce heart disease risk</span>
February 10, 2025

Seven tips to reduce heart disease risk

Our hearts are the engines that power our lives, so taking care of them should be a top priority. Unfortunately, heart disease is still the leading cause of mortality in the United States. But the good news is it’s also largely preventable through simple lifestyle changes. February is American Heart Month and a great time to look at the modifiable risk factors for developing this disease. After all, the key to a healthier heart is largely in your hands.
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<span>Labcorp Announces 2024 Fourth Quarter and Full Year Results</span>
February 6, 2025

Labcorp Announces 2024 Fourth Quarter and Full Year Results

Company Provides 2025 Guidance Results from Continuing Operations versus last year: Revenue: Q4 of $3.33 billion vs $3.03 billion ; Full year of $13.01 billion vs $12.16 billion Diluted EPS: Q4 of $1.70 vs $(1.95) ; Full year of $8.84 vs $4.33 Adjusted EPS: Q4 of $3.45 vs $3.30 ; Full year of
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<span>How lab data enables more accurate patient coding for value-based care success</span>
February 7, 2025

How lab data enables more accurate patient coding for value-based care success

As the healthcare landscape continues to evolve, value-based care is playing a pivotal role in enhancing patient outcomes while effectively managing costs. For providers engaged in value-based care programs, accurate patient coding isn’t just important—it's essential for achieving success. Unfortunately, many ACOs and Medicare Advantage networks face significant challenges due to coding inaccuracies, which can hinder their progress toward performance goals and cost savings. In this blog, Labcorp's Brian Buesing, Vice President of commercial efforts for large physician organizations and value-based care networks, explores how integrating robust laboratory data can streamline coding practices and ultimately lead to better health outcomes and financial performance.
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