Test Details
Methodology
Polymerase chain reaction (PCR) amplification and viral culture. Trofile™ is a registered trademark of Monogram Biosciences.
Result Turnaround Time
29 - 33 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as Selzentry™ (maraviroc).
Limitations
This procedure should be used for patients with documented HIV-1 infection and undetectable viral loads.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
References
Specimen Requirements
Specimen
Whole blood, frozen
Volume
4 mL
Container
Lavender-top (EDTA) tube
Collection Instructions
Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen. To avoid delays in turnaround time, when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze.
Causes for Rejection
Insufficient volume; heparinized plasma; nonfrozen specimen
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 829670 | Trofile(R) DNA | 550341 | Trofile(R) DNA PDF | 51969-4 | ||
| 829670 | Trofile(R) DNA | 550347 | Tropotype: | 80690-1 | ||
| 829670 | Trofile(R) DNA | 829671 | Trofile(R) DNA | 50790-5 | ||
| 829670 | Trofile(R) DNA | 829672 | Trofile(R) DNA Interpretation | 62364-5 | ||
| Order Code | 829670 | |||||
| Order Code Name | Trofile(R) DNA | |||||
| Order Loinc | ||||||
| Result Code | 550341 | |||||
| Result Code Name | Trofile(R) DNA PDF | |||||
| UofM | ||||||
| Result LOINC | 51969-4 | |||||
| Order Code | 829670 | |||||
| Order Code Name | Trofile(R) DNA | |||||
| Order Loinc | ||||||
| Result Code | 550347 | |||||
| Result Code Name | Tropotype: | |||||
| UofM | ||||||
| Result LOINC | 80690-1 | |||||
| Order Code | 829670 | |||||
| Order Code Name | Trofile(R) DNA | |||||
| Order Loinc | ||||||
| Result Code | 829671 | |||||
| Result Code Name | Trofile(R) DNA | |||||
| UofM | ||||||
| Result LOINC | 50790-5 | |||||
| Order Code | 829670 | |||||
| Order Code Name | Trofile(R) DNA | |||||
| Order Loinc | ||||||
| Result Code | 829672 | |||||
| Result Code Name | Trofile(R) DNA Interpretation | |||||
| UofM | ||||||
| Result LOINC | 62364-5 |