Nontuberculous Slowly-growing Mycobacterium Susceptibility−Broth Dilution

Slowly-growing mycobacteria, other than M. tuberculosis or M. avium, isolated from a primary clinical specimen, on a submitted AFB conventional solid medium, or an AFB broth medium

Pure culture isolate on an AFB conventional solid medium or a minimum of 1 mL of AFB broth medium

Conventional or broth medium, tightly sealed, in etiologic agent packaging

Determine the susceptibility of nontuberculous slowly-growing mycobacterial isolates to a profile of antimycobacterial agents. Clinical breakpoints for M. kansasii and Nontuberculosis Mycobacteria other than M. avium Complex are the same. Some fastidious isolates may not exhibit adequate growth for susceptibility testing (M. genvense, M. haemophilum). Others such as M. gordonae are rarely clinically relevant and susceptibility testing is not recommended. If patients are not responding to several months of therapy, repeat susceptibility testing is recommended.

Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures. An organism identification is required prior to reporting susceptibility results.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Sensititre® broth microdilution (MIC)