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For hours, walk-ins and appointments.Acid-fast (Mycobacteria) Antibiotic Susceptibilities
CPT:
87190(x4). Variable depending on identification.
Synonyms
- AFB Susceptibility Testing
- Rapid-grower Susceptibility Testing
- Susceptibility Testing, AFB
- TB Susceptibility Testing
Test Includes
Antimycobacterial agents tested against isolates at appropriate concentrations and drugs depending on identification of the isolate. Identification is required to perform or provide an accurate interpretation for susceptibility testing, it will be done at an additional charge automatically.
Special Instructions
Culture must be in special etiologic agent packaging for shipment to LabCorp.
Expected Turnaround Time
40 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Specimen Requirements
Specimen
Isolated mycobacteria from primary clinical specimen on media slant or in broth
Container
Media slant, tightly sealed, in etiologic agent packaging
Storage Instructions
Maintain culture at room temperature.
Causes for Rejection
Specimen received leaking or in broken transport tube or vial; specimen received in expired transport media; mixed culture; unlabeled culture or name discrepancy between specimen and request label
Test Details
Use
Determine the susceptibility of the isolated organism to a profile of antimycobacterial agents
Limitations
Susceptibilities cannot be reported if the organism fails to grow on test media.
Methodology
Bactec®, Sensititre® broth Microdilution (MIC), or conventional agar proportion
Additional Information
Susceptibilities should be performed on the first organism isolated from a patient. Additional susceptibility testing may be needed if the patient is still symptomatic or culture positive after several months of appropriate treatment. Organism identification is needed prior to the initiation of susceptibility testing so that the appropriate therapeutic drugs are utilized.
References
Clinical Laboratory Standards Institute (CLSI). Performance Standards for Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 1st ed. CLSI supplement M62. Wayne, PA: CLSI; 2018.
Clinical Laboratory Standards Institute (CLSI). Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 3rd ed. CLSI standard M24. Wayne, PA: CLSI; 2018.
Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007 Feb 15;175(4):367-416.17277290
Woods GL, Lin SYG, Brown BA, Desmond EP. Susceptibility Test Methods: Mycobacteria, Nocardia and Other Actinomycetes. Manual of Clinical Microbiology, 12th ed. 2018; 78:1398-1419.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 088161 | AFB Antibiotic Suscep | 9825-1 | 088161 | AFB Antibiotic Suscep | 9825-1 |
| Reflex Table for AFB Antibiotic Suscep | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080543 | Result | 080544 | Result 1 | 9825-1 | |
| Reflex Table for AFB Antibiotic Suscep | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080543 | Result | 080545 | Result 2 | N/A | |
| Reflex Table for AFB Antibiotic Suscep | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080543 | Result | 080546 | Result 3 | N/A | |
| Reflex Table for AFB Antibiotic Suscep | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080543 | Result | 080547 | Result 4 | N/A | |
| Reflex Table for AFB Antibiotic Suscep | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080543 | Result | 080548 | Antimicrobial Susceptibility | 23658-8 | |
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