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Acid-fast (Mycobacteria) Antibiotic Susceptibilities

Test Number 088161
Test number copied
CPT 87190(x4). Variable depending on identification.
Synonyms
  • AFB Susceptibility Testing
  • Rapid-grower Susceptibility Testing
  • Susceptibility Testing, AFB
  • TB Susceptibility Testing

Test Details

Methodology

Bactec®, Sensititre® broth Microdilution (MIC), or conventional agar proportion

Result Turnaround Time

40 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Test Includes

Antimycobacterial agents tested against isolates at appropriate concentrations and drugs depending on identification of the isolate. Identification is required to perform or provide an accurate interpretation for susceptibility testing, it will be done at an additional charge automatically.

Use

Determine the susceptibility of the isolated organism to a profile of antimycobacterial agents

Special Instructions

Culture must be in special etiologic agent packaging for shipment to LabCorp.

Limitations

Susceptibilities cannot be reported if the organism fails to grow on test media.

References

Clinical Laboratory Standards Institute (CLSI). Performance Standards for Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 1st ed. CLSI supplement M62. Wayne, PA: CLSI; 2018.
Clinical Laboratory Standards Institute (CLSI). Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 3rd ed. CLSI standard M24. Wayne, PA: CLSI; 2018.
Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007 Feb 15;175(4):367-416.17277290
Woods GL, Lin SYG, Brown BA, Desmond EP. Susceptibility Test Methods: Mycobacteria, Nocardia and Other Actinomycetes. Manual of Clinical Microbiology, 12th ed. 2018; 78:1398-1419.

Custom Additional Information

Susceptibilities should be performed on the first organism isolated from a patient. Additional susceptibility testing may be needed if the patient is still symptomatic or culture positive after several months of appropriate treatment. Organism identification is needed prior to the initiation of susceptibility testing so that the appropriate therapeutic drugs are utilized.

Specimen Requirements

Specimen

Isolated mycobacteria from primary clinical specimen on media slant or in broth

Container

Media slant, tightly sealed, in etiologic agent packaging

Storage Instructions

Maintain culture at room temperature.

Causes for Rejection

Specimen received leaking or in broken transport tube or vial; specimen received in expired transport media; mixed culture; unlabeled culture or name discrepancy between specimen and request label

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
088161 AFB Antibiotic Suscep 9825-1 088161 AFB Antibiotic Suscep 9825-1
Order Code088161
Order Code NameAFB Antibiotic Suscep
Order Loinc9825-1
Result Code088161
Result Code NameAFB Antibiotic Suscep
UofM
Result LOINC9825-1
Reflex Table for AFB Antibiotic Suscep
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080543 Result 080544 Result 1 9825-1
Reflex 1
Order Code080543
Order NameResult
Result Code080544
Result NameResult 1
UofM
Result LOINC9825-1
Reflex Table for AFB Antibiotic Suscep
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080543 Result 080545 Result 2 N/A
Reflex 1
Order Code080543
Order NameResult
Result Code080545
Result NameResult 2
UofM
Result LOINCN/A
Reflex Table for AFB Antibiotic Suscep
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080543 Result 080546 Result 3 N/A
Reflex 1
Order Code080543
Order NameResult
Result Code080546
Result NameResult 3
UofM
Result LOINCN/A
Reflex Table for AFB Antibiotic Suscep
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080543 Result 080547 Result 4 N/A
Reflex 1
Order Code080543
Order NameResult
Result Code080547
Result NameResult 4
UofM
Result LOINCN/A
Reflex Table for AFB Antibiotic Suscep
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080543 Result 080548 Antimicrobial Susceptibility 23658-8
Reflex 1
Order Code080543
Order NameResult
Result Code080548
Result NameAntimicrobial Susceptibility
UofM
Result LOINC23658-8