Find Locations
For hours, walk-ins and appointments.Nocardia, Aerobic Actinomycetes Susceptibility (AST)−Broth Dilution
CPT:
87186
Synonyms
- Nocardia Susceptibility Testing
- AFB Susceptibility Testing
- Susceptibility Testing, Nocardia
Test Includes
Susceptibility testing for amikacin, amoxicillin/clavulanic acid, ceftriaxone, ciprofloxacin, clarithromycin, doxycycline, imipenem, linezolid, minocycline, moxifloxacin, trimethoprim/sulfamethoxazole, and tobramycin. MIC values will be reported with CLSI interpretive comments.
Expected Turnaround Time
14 - 28 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Nocardia species or other aerobic actinomycetes isolated from a primary clinical specimen, on a submitted conventional solid medium (ie, Lowenstein-Jensen [LJ] slant, Sabouraud dextrose [SAB] slant, or similar)
Volume
Pure culture isolate on a conventional solid medium
Container
Conventional medium, tightly sealed, in etiologic agent packaging
Storage Instructions
Maintain media at room temperature.
Causes for Rejection
Broken transport tube or vial; specimen received in expired transport medium; mixed culture; unlabeled culture or name discrepancy between specimen and request label
Test Details
Use
Determine the susceptibility of Nocardia species and/or other aerobic Actinomycetes isolates to a profile of antimicrobial agents. Routine susceptibility testing of Nocardia isolates is recommended since the Nocardia genus contains a heterogeneous group of organisms that has variable antibiotic susceptibilities.
Limitations
Susceptibilities cannot be reported if the organism fails to grow in the test medium. Susceptibilities cannot be performed on mixed cultures.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Sensititre® broth microdilution (MIC)
References
Clinical Laboratory Standards Institute (CLSI). Performance Standards for Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 1st ed. CLSI supplement M62. Wayne, PA: CLSI; 2018.
Clinical Laboratory Standards Institute (CLSI). Susceptibility Testing of Mycobacteria, Nocardia spp., and Other Aerobic Actinomycetes. 3rd ed. CLSI standard M24. Wayne, PA: CLSI; 2018.
Woods GL, Lin SYG, Brown BA, Desmond EP. Susceptibility Test Methods: Mycobacteria, Nocardia and Other Actinomycetes. Manual of Clinial Microbiology, 12th ed. 2018; 78:1398-1419.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 182858 | Organism ID | N/A | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998537 | Amikacin | 12-5 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998538 | Amoxicillin/CA | 20-8 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998539 | Ceftriaxone | 141-2 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998540 | Ciprofloxacin | 185-9 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998541 | Clarithromycin | 189-1 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998216 | Doxycycline | 225-3 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998543 | Imipenem | 279-0 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998544 | Linezolid | 29254-0 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998545 | Minocycline | 335-0 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998217 | Moxifloxacin | 31037-5 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998547 | Tobramycin | 508-2 | |
| 182857 | Nocardia Susceptibility Broth | 50545-3 | 998546 | Trimethoprim/Sulfa | 516-5 |
| Reflex Table for Organism ID | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 000000 | Antimicrobial Susceptibility | 000000 | Antimicrobial Susceptibility | N/A | |
© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.
CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf