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Gestational Diabetes Screen (ACOG Recommendations)

CPT 82950
Synonyms
  • Glucose Tolerance, Gestational Diabetes (One-hour)

Test Details

Methodology

Enzymatic

Result Turnaround Time

Within 1 day

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Test Includes

50-gram one-hour glucose tolerance challenge

Use

Screening test for gestational diabetes

Special Instructions

The patient need not be fasting. The one-hour screen requires a 50-gram oral glucose load or 50-gram "Fresh Test" product (https://www.labcorp.com/provider-services/programs/partners-pregnancy) followed by a plasma glucose determination one hour later. (Refer to Additional Information below.) See the online Endocrine Appendix: Glucose Tolerance: Gestational Diabetes Mellitus for further information regarding glucose tolerance testing.

Contraindications

Patient with known history of diabetes mellitus

Footnotes

1. Labcorp internal studies.
2. American College of Obstetricians and Gynecologists. Committee on Practice Bulletins—Obstetrics. Practice Bulletin No. 137: Gestational diabetes mellitus. Obstet Gynecol. 2013 Aug;122(2 Pt 1):406-416.23969827
3. American Diabetes Association. Standards of Medical Care in Diabetes—2015: Summary of revisions. Diabetes Care. 2015 Jan;38(Suppl 1):S4.25537706

Custom Additional Information

The American College of Obstetricians and Gynecologists (ACOG) recommends that all pregnant women be screened for gestational diabetes mellitus (GDM)—whether by patient history, clinical risk factors, or with a 50-gram, one-hour loading test at 24 to 28 weeks of gestation to determine blood glucose levels—and suggests relying on the result of the 100-gram, three-hour oral glucose tolerance test for diagnosis (often referred to as a "two-step" method).2

The American Diabetes Association (ADA)3 released standards that vary from the ACOG recommendations. The ADA recommends a simplified "one-step" approach to the screen and diagnosis of gestational diabetes mellitus with a 75-gram, two-hour glucose tolerance test. The LabCorp test according to the ADA recommendations is Gestational Glucose Tolerance Screening and Diagnostics Test (Two-hour, ADA Recommendations) [101000]. A glucose tolerance screen glucose threshold >139 mg/dL after a 50-gram load identifies approximately 80% of women with gestational diabetes mellitus, while the sensitivity is further increased to approximately 90% by a threshold >129 mg/dL. Perform a diagnostic 100-gram oral glucose tolerance test (102004) on a separate day on women who exceed the chosen threshold on 50-gram screening.

Specimen Requirements

Specimen

Serum or plasma

Volume

1 mL serum or plasma each tube

Minimum Volume

0.5 mL serum or plasma each tube

Container

Gel-barrier tube or gray-top (sodium fluoride/potassium oxalate plasma) tube

Collection Instructions

Note: A fasting blood sample is not required. Draw one hour specimen after a 50-gram glucose challenge. The patient should remain seated and not smoke throughout the test. Submit 1 mL serum or plasma for one-hour specimen. Separate serum or plasma from cells within 45 minutes of venipuncture. Gray-top tubes only, may be submitted without centrifugation. Label tube with patient's name and collection time interval (i.e., one-hour).

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Reference Range

70−139 mg/dL

Storage Instructions

Maintain specimen at room temperature.1

Patient Preparation

None; glucose challenge is administered without regard to time of day or time of last meal.

Causes for Rejection

Frozen gray-top tube (frozen plasma from gray-top is acceptable); stressed patient (surgery, infection, corticosteroids) should not have GTT; specimen not labeled with collection time intervals (i.e., one hour)

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
102277 Gest. Diabetes 1-Hr Screen 1504-0 102285 Gestational Diabetes Screen mg/dL 1504-0
Order Code102277
Order Code NameGest. Diabetes 1-Hr Screen
Order Loinc1504-0
Result Code102285
Result Code NameGestational Diabetes Screen
UofMmg/dL
Result LOINC1504-0