Foresight: Start with the end in mind
If you don’t know where you are going, how will you get there? Articulating the destination of your therapeutic is essential for determining whether the asset in development is commercially viable and meets required milestones. A vital roadmap to your end destination is the target product profile (TPP). When used early and proactively, the TTP can propel your discovery program forward.
Target product profile (TPP)
The TPP is a planning tool for therapeutic candidates based on FDA guidelines that define the optimal and minimally acceptable profile of the final marketed product.2 The TPP defines the goal of the therapy for patients and provides a document summarizing the vision and strategy for the product. This living document, which is developed early in development and updated often, provides the framework for making decisions on lead candidate and formulation selection. It also defines what studies need to be conducted when, minimizing risk and ultimately accelerating regulatory acceptance.
Funding agencies and investors will look for a TPP when making funding decisions because the TPP demonstrates your competence as a developer, articulates the vision for the asset and inspires confidence in the product development plan. Many are looking to fund a specific drug product profile, and the TPP can help indicate your asset’s competitive advantage over current therapies.
Labcorp’s foresight
Labcorp’s team of directors of Drug Development and Regulatory Strategy (DD&RS) can help guide you in developing a TPP for successful drug discovery, lead candidate selection and commercialization. Explore our early phase development solutions.
Keeping ahead of innovations and regulatory changes
Labcorp’s DD&RS team has a clear forward-focus: they are up to date with scientific innovations and work frequently with regulatory authorities to understand changing regulatory environments. That makes them finely attuned to ways of avoiding potential pitfalls and challenges that could arise in your preclinical development plan.
The DD&RS team can create a structured, risk-mitigated plan designed to deliver the critical proof of concept data when you need it. But it’s not just about planning; Labcorp supports study execution excellence as well. With a global team of more than 4,700 staff operating from more than 20 laboratory sites, we have the know-how, capacity and flexibility to run a wide range of the essential drug discovery activities that you might need.
Going beyond the data to help you secure future funding
As well as collaborating with you to develop a sound preclinical discovery plan, we can also help you showcase the value of your asset to potential investors. Using MarketPlace, Labcorp's digital partnering platform, your assets can be presented to potential partners who are seeking to license or acquire innovative medicines. Whether you are looking for funding or even acquisition, MarketPlace can accelerate strategic conversations and propel you toward your partnering goals. Explore MarketPlace.
“MarketPlace gave us tremendous exposure across the industry and facilitated meaningful strategic collaboration discussions. We were able to strike a co-development deal with our lead asset within 90 days of publishing to MarketPlace.”
-Chief Business Officer, U.S. Biotech