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Dextromethorphan (DM), Serum or Plasma

CPT 80299
Synonyms
  • Methorphan

Test Details

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Result Turnaround Time

5 - 10 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

Therapeutic drug management; detect presence of dextromethorphan, an over-the-counter cough suppressant with abuse potential

Specimen Requirements

Specimen

Serum or plasma

Volume

2 mL

Minimum Volume

0.5 mL

Container

Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Collection Instructions

Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Reference Range

2.0−6.0 ng/mL

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen. Specimen is stable three days at room temperature; two weeks refrigerated or frozen.

Patient Preparation

Trough levels are most reproducible.

Causes for Rejection

Gel-barrier tubes

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
811893 Dextromethorphan 808283 Dextromethorphan (DM) ng/ml 13623-4
Order Code811893
Order Code NameDextromethorphan
Order Loinc
Result Code808283
Result Code NameDextromethorphan (DM)
UofMng/ml
Result LOINC13623-4