Test Details
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Therapeutic drug management
Specimen Requirements
Specimen
Serum or plasma
Volume
2 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.
Collection Instructions
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Reference Range
Carbamazepine: 4.0−12.0 µg/mL; carbamazepine-10,11-epoxide: 0.4−4.0 µg/mL
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Patient Preparation
Trough levels are most reproducible.
Causes for Rejection
Gel-barrier tubes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 803189 | Carbamazepine + Carb Epoxide | 808278 | Carabamazepine | ug/ml | 3432-2 | |
| 803189 | Carbamazepine + Carb Epoxide | 808279 | Carbamazepine-10,11-Epoxide | ug/ml | 9415-1 | |
| Order Code | 803189 | |||||
| Order Code Name | Carbamazepine + Carb Epoxide | |||||
| Order Loinc | ||||||
| Result Code | 808278 | |||||
| Result Code Name | Carabamazepine | |||||
| UofM | ug/ml | |||||
| Result LOINC | 3432-2 | |||||
| Order Code | 803189 | |||||
| Order Code Name | Carbamazepine + Carb Epoxide | |||||
| Order Loinc | ||||||
| Result Code | 808279 | |||||
| Result Code Name | Carbamazepine-10,11-Epoxide | |||||
| UofM | ug/ml | |||||
| Result LOINC | 9415-1 |