Test Details
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
7 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Amitriptyline; clomipramine; cyclobenzaprine; desipramine; desmethylclomipramine; desmethyldoxepin; desmethylsertraline; doxepin; fluoxetine; imipramine, maprotiline; norfluoxetine; nortriptyline, paroxetine, protriptyline; sertraline; trimipramine
Use
Detect presence of antidepressant drugs
Specimen Requirements
Specimen
Serum or plasma
|
Serum or plasma |
Volume
3 mL
Minimum Volume
600 μL
Container
Serum or plasma (preferred): Red-top tube or green-top (heparin) tube; gel-barrier tubes are not acceptable.
Serum or plasma (preferred): Red-top tube or green-top (heparin) tube; gel-barrier tubes are not acceptable. Whole blood (acceptable but not preferred): Lavender-top (EDTA) tube, gray-top (sodium fluoride) tube or green-top (heparin) tub |
Serum or plasma (preferred): Red-top tube or green-top (heparin) tube; gel-barrier tubes are not acceptabl e. |
Collection Instructions
Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Causes for Rejection
Gel-barrier tubes; whole blood
Gel-barrier tubes |
Gel-barrier tubes; whole blood |
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791491 | Submitted Specimen Type: | 31208-2 | |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 803273 | Antidepressant Screen | 16389-9 | |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791492 | Amitriptyline | ng/ml | 35636-0 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791493 | Nortriptyline | ng/ml | 35627-9 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791494 | Amitriptyline+Nortriptyline | ng/ml | 3335-7 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791495 | Imipramine | ng/ml | 3690-5 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791496 | Desipramine | ng/ml | 35606-3 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791497 | Imipramine+Desipramine | ng/ml | 9627-1 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791498 | Sertraline | ng/ml | 6906-2 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791499 | Desmethylsertraline | ng/ml | 6897-3 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791501 | Fluoxetine | ng/ml | 35610-5 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791502 | Norfluoxetine | ng/ml | 35624-6 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791503 | Fluoxetine+Norfluoxetine | ng/ml | 10339-0 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791504 | Clomipramine | ng/ml | 35602-2 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791505 | Desmethylclomipramine | ng/ml | 35621-2 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791506 | Doxepin | ng/ml | 35609-7 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791507 | Desmethyldoxepin | ng/ml | 35623-8 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791508 | Doxepin+Desmethyldoxepin | ng/ml | 3582-4 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791509 | Maprotiline | ng/ml | 3735-8 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791511 | Protriptyline | ng/ml | 3999-0 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791512 | Trimipramine | ng/ml | 4083-2 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791616 | Paroxetine | ng/ml | 9699-0 |
| 791490 | Quant Antidepressant Drug Scr | 80148-0 | 791514 | Cyclobenzaprine | ng/ml | 35604-8 |
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791491 | |||||
| Result Code Name | Submitted Specimen Type: | |||||
| UofM | ||||||
| Result LOINC | 31208-2 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 803273 | |||||
| Result Code Name | Antidepressant Screen | |||||
| UofM | ||||||
| Result LOINC | 16389-9 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791492 | |||||
| Result Code Name | Amitriptyline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35636-0 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791493 | |||||
| Result Code Name | Nortriptyline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35627-9 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791494 | |||||
| Result Code Name | Amitriptyline+Nortriptyline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 3335-7 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791495 | |||||
| Result Code Name | Imipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 3690-5 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791496 | |||||
| Result Code Name | Desipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35606-3 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791497 | |||||
| Result Code Name | Imipramine+Desipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 9627-1 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791498 | |||||
| Result Code Name | Sertraline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 6906-2 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791499 | |||||
| Result Code Name | Desmethylsertraline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 6897-3 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791501 | |||||
| Result Code Name | Fluoxetine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35610-5 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791502 | |||||
| Result Code Name | Norfluoxetine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35624-6 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791503 | |||||
| Result Code Name | Fluoxetine+Norfluoxetine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 10339-0 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791504 | |||||
| Result Code Name | Clomipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35602-2 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791505 | |||||
| Result Code Name | Desmethylclomipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35621-2 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791506 | |||||
| Result Code Name | Doxepin | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35609-7 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791507 | |||||
| Result Code Name | Desmethyldoxepin | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35623-8 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791508 | |||||
| Result Code Name | Doxepin+Desmethyldoxepin | |||||
| UofM | ng/ml | |||||
| Result LOINC | 3582-4 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791509 | |||||
| Result Code Name | Maprotiline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 3735-8 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791511 | |||||
| Result Code Name | Protriptyline | |||||
| UofM | ng/ml | |||||
| Result LOINC | 3999-0 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791512 | |||||
| Result Code Name | Trimipramine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 4083-2 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791616 | |||||
| Result Code Name | Paroxetine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 9699-0 | |||||
| Order Code | 791490 | |||||
| Order Code Name | Quant Antidepressant Drug Scr | |||||
| Order Loinc | 80148-0 | |||||
| Result Code | 791514 | |||||
| Result Code Name | Cyclobenzaprine | |||||
| UofM | ng/ml | |||||
| Result LOINC | 35604-8 |