Test Details
Methodology
In situ hybridization
Result Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
DNA probe hybridization for EBV in formalin-fixed, paraffin-embedded tissue
Use
Detect EBV DNA sequences in tissue sections; adjunct to histopathology
Special Instructions
Please direct any questions regarding this test to oncology customer service at 800-345-4363.
Limitations
Failure to detect target DNA may result from several factors, eg, improper sampling, handling, and/or fixative of the specimen, or target DNA below the sensitivity limits of the assay; therefore, lack of staining does not necessarily imply the absence of target DNA.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.
Specimen Requirements
Specimen
Formalin-fixed, paraffin-embedded (FFPE) tissue biopsy. Tissue biopsies should be fixed in 10% neutral-buffered formalin and embedded in paraffin within 72 hours. Do not submit frozen tissue or substitute other fixatives. For tissues submitted in formalin, please provide the appropriate gross/microscopic description indicating the number, type, and sites of the tissue submitted.
Container
Submit paraffin block in crushproof container. Submit fresh tissue in a sterile container in 10% neutral-buffered formalin.
Collection Instructions
Tissue biopsies should be fixed in 10% neutral buffered formalin and embedded in paraffin within 72 hours. Do not submit frozen tissue or substitute other fixatives. For tissues submitted in formalin, please provide appropriate gross/microscopic description indicating the number, type, and site of the tissue(s) submitted.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Insufficient tissue; improper fixation; inappropriate fixative
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 550913 | Epstein-Barr Virus, DNA Probe | 5004-7 | 550919 | EBV, DNA Probe | 5004-7 | |
| Order Code | 550913 | |||||
| Order Code Name | Epstein-Barr Virus, DNA Probe | |||||
| Order Loinc | 5004-7 | |||||
| Result Code | 550919 | |||||
| Result Code Name | EBV, DNA Probe | |||||
| UofM | ||||||
| Result LOINC | 5004-7 |