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Hepatitis C Virus (HCV), Quantitative, Real-time PCR (Graphical)
CPT:
87522
Synonyms
- HCV RNA Quantitation, TaqMan®
Special Instructions
Submit the patient's Social Security number for serial monitoring. To order this test without the serial monitor service, order Hepatitis C Virus (HCV), Quantitative, Real-time PCR (Nongraphical) [550080].
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
For more information, please view the literature below.
LabCorp offers the leading HCV menu for complete care decisions
Specimen Requirements
Specimen
Serum or plasma
Volume
2.5 mL
Minimum Volume
700 μL (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube, lavender-top (EDTA) tube, or plasma preparation tube (PPT™)
Collection
Centrifuge sample within 24 hours of collection. Transfer serum/plasma to a screw-cap polypropylene transport tube. Ship frozen (preferred). Plasma from a PPT™ can be frozen and shipped in situ. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit a separate frozen specimen for each test requested.
Storage Instructions
Freeze (preferred) or refrigerate.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 24 hours (stability provided by manufacturer or literature reference) |
Refrigerated | 72 hours (stability provided by manufacturer or literature reference) |
Frozen | 6 weeks (stability provided by manufacturer or literature reference) |
Causes for Rejection
Incorrect anticoagulant; PPT™ not centrifuged
Test Details
Use
Determine the number of international units (IU) of hepatitis C virus (HCV) RNA per milliliter in serum or plasma in known HCV-positive patients
Limitations
The quantifiable range of the assay is 15 IU/mL to 100,000,000 IU/mL.
Methodology
Cobas® HCV (Roche Molecular Systems)
References
Yao JD, Young S, Heilek GM, et al. Diagnosis and monitoring of HCV infection using the cobas® HCV test for use on the cobas® 6800/8800 systems. J Clin Virol. 2018 May;102:63-69.29518694
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 550070 | HCV RT-PCR, Quant (Graph) | 11011-4 | 550266 | Hepatitis C Quantitation | IU/mL | 11011-4 |
| 550070 | HCV RT-PCR, Quant (Graph) | 11011-4 | 550259 | HCV log10 | log10 IU/mL | 38180-6 |
| 550070 | HCV RT-PCR, Quant (Graph) | 11011-4 | 550307 | Test Information: | N/A | |
| 550070 | HCV RT-PCR, Quant (Graph) | 11011-4 | 511958 | 80563-0 |
| Reflex Table for Hepatitis C Quantitation | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 550265 | HCV RNA (International Units) | 550263 | HCV RNA (International Units) | IU/mL | 11011-4 |
| Reflex Table for Hepatitis C Quantitation | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 550265 | HCV RNA (International Units) | 550264 | HCV log10 | log10 IU/mL | 38180-6 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf