Test Details
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Result Turnaround Time
7 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Anti-CarP antibodies may be positive in about 10% of early RA patients who are RF-negative and anti-CCP-negative and may be present years before the onset of RA symptoms.1,2 Anti-CarP is associated with more active disease and higher risk of developing joint erosions.1 Anti-CarP levels especially in combination with RF- and Anti-CCP-positivity may predict joint erosion and radiographic progression.1
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube; serum from red-top tube; serum from a gel tube; or serum gel tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Storage Instructions
Refrigerate or freeze.
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520311 | Anti-CarP Ab | 66445-8 | 520312 | Anti-CarP Ab | Units | 66445-8 |
| Order Code | 520311 | |||||
| Order Code Name | Anti-CarP Ab | |||||
| Order Loinc | 66445-8 | |||||
| Result Code | 520312 | |||||
| Result Code Name | Anti-CarP Ab | |||||
| UofM | Units | |||||
| Result LOINC | 66445-8 |