Test Details
Methodology
See individual test components.
Result Turnaround Time
14 - 21 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Anti-CCP Ab IgG/IgA; Anti-EJ Ab; Anti-Jo-1 Ab; Anti-Ku Ab; Anti-MDA5 Ab; Anti-OJ Ab; Anti-PL-7 Ab; Anti-PL-12 Ab; Anti-PM/Scl-100 Ab; Anti-Scl-70; Anti-SSA 52 kD Ab; Anti-SRP Ab; Rheumatoid Factor IgM by Turb.
ANA by IFA (If positive, reflexes to Anti-dsDNA by Farr; Anti-La (SS-B) Ab; Anti-Ro (SS-A) Ab; Anti-Sm Ab; Anti-U1 RNP Ab.
ANCA (If positive, reflexes to Anti-MPO Ab and Anti-PR3 Ab).
Use
Interstitial Lung Disease (ILD) can complicate several collagen vascular diseases, including Systemic Sclerosis (SS),Sjorgens's Syndrome (SjS), Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIM), and ANCA-Associated Vasculitis (AAV). Identifying an underlying autoimmune disorder in ILD patients has critical importance in therapuetic decision-making and has a meaningful impact on prognosis.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Serum
Volume
4 mL
Minimum Volume
3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Stability Requirements
Temperature | Period |
---|---|
Room temperature | 1 day |
Refrigerated | 8 days |
Frozen | 8 days |
Storage Instructions
Refrigerate.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
LOINC® Map
Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
---|---|---|---|---|---|---|
520210 | ILDdx Profile (RDL) | 520132 | Rheumatoid Factor by Turb RDL | IU/mL | 11572-5 | |
520210 | ILDdx Profile (RDL) | 520226 | Anti-CCP Ab, IgG + IgA (RDL) | Units | 57093-7 | |
520210 | ILDdx Profile (RDL) | 520259 | Anti-Jo-1 Ab (RDL) | Units | 35333-4 | |
520210 | ILDdx Profile (RDL) | 520046 | Anti-PL-7 Ab (RDL) | 33772-5 | ||
520210 | ILDdx Profile (RDL) | 520049 | Anti-PL-12 Ab (RDL) | 33771-7 | ||
520210 | ILDdx Profile (RDL) | 520027 | Anti-EJ Ab (RDL) | 45149-2 | ||
520210 | ILDdx Profile (RDL) | 520029 | Anti-OJ Ab (RDL) | 45152-6 | ||
520210 | ILDdx Profile (RDL) | 520040 | Anti-SRP Ab (RDL) | 33921-8 | ||
520210 | ILDdx Profile (RDL) | 520251 | Anti-MDA-5 Ab (CADM-140)(RDL) | Units | 103691-2 | |
520210 | ILDdx Profile (RDL) | 520221 | Anti-Scl-70 Ab (RDL) | Units | 26975-3 | |
520210 | ILDdx Profile (RDL) | 520228 | Anti-PM/Scl-100 Ab (RDL) | Units | 31562-2 | |
520210 | ILDdx Profile (RDL) | 520031 | Anti-Ku Ab (RDL) | 18484-6 | ||
520210 | ILDdx Profile (RDL) | 520253 | Anti-SS-A 52kD Ab, IgG (RDL) | Units | 70257-1 | |
520210 | ILDdx Profile (RDL) | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | ||
520210 | ILDdx Profile (RDL) | 520255 | ANCA by IFA (RDL) | 35279-9 | ||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520132 | |||||
Result Code Name | Rheumatoid Factor by Turb RDL | |||||
UofM | IU/mL | |||||
Result LOINC | 11572-5 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520226 | |||||
Result Code Name | Anti-CCP Ab, IgG + IgA (RDL) | |||||
UofM | Units | |||||
Result LOINC | 57093-7 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520259 | |||||
Result Code Name | Anti-Jo-1 Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 35333-4 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520046 | |||||
Result Code Name | Anti-PL-7 Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 33772-5 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520049 | |||||
Result Code Name | Anti-PL-12 Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 33771-7 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520027 | |||||
Result Code Name | Anti-EJ Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 45149-2 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520029 | |||||
Result Code Name | Anti-OJ Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 45152-6 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520040 | |||||
Result Code Name | Anti-SRP Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 33921-8 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520251 | |||||
Result Code Name | Anti-MDA-5 Ab (CADM-140)(RDL) | |||||
UofM | Units | |||||
Result LOINC | 103691-2 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520221 | |||||
Result Code Name | Anti-Scl-70 Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 26975-3 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520228 | |||||
Result Code Name | Anti-PM/Scl-100 Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 31562-2 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520031 | |||||
Result Code Name | Anti-Ku Ab (RDL) | |||||
UofM | ||||||
Result LOINC | 18484-6 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520253 | |||||
Result Code Name | Anti-SS-A 52kD Ab, IgG (RDL) | |||||
UofM | Units | |||||
Result LOINC | 70257-1 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520073 | |||||
Result Code Name | Anti-Nuclear Ab by IFA (RDL) | |||||
UofM | ||||||
Result LOINC | 42254-3 | |||||
Order Code | 520210 | |||||
Order Code Name | ILDdx Profile (RDL) | |||||
Order Loinc | ||||||
Result Code | 520255 | |||||
Result Code Name | ANCA by IFA (RDL) | |||||
UofM | ||||||
Result LOINC | 35279-9 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520341 | Repeat Anti-Scl-70 | 520341 | Repeat Anti-Scl-70 | 5348-8 | |
Reflex 1 | ||||||
Order Code | 520341 | |||||
Order Name | Repeat Anti-Scl-70 | |||||
Result Code | 520341 | |||||
Result Name | Repeat Anti-Scl-70 | |||||
UofM | ||||||
Result LOINC | 5348-8 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520074 | Homogeneous Pattern | 20398-4 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520074 | |||||
Result Name | Homogeneous Pattern | |||||
UofM | ||||||
Result LOINC | 20398-4 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520076 | Nucleolar Pattern | 20399-2 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520076 | |||||
Result Name | Nucleolar Pattern | |||||
UofM | ||||||
Result LOINC | 20399-2 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520233 | Speckled Pattern | 20401-6 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520233 | |||||
Result Name | Speckled Pattern | |||||
UofM | ||||||
Result LOINC | 20401-6 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520234 | Centromere Pattern | 53993-2 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520234 | |||||
Result Name | Centromere Pattern | |||||
UofM | ||||||
Result LOINC | 53993-2 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520235 | Spindle Apparatus Pattern | 53003-0 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520235 | |||||
Result Name | Spindle Apparatus Pattern | |||||
UofM | ||||||
Result LOINC | 53003-0 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520236 | Nuclear Membrane Pattern | 54006-2 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520236 | |||||
Result Name | Nuclear Membrane Pattern | |||||
UofM | ||||||
Result LOINC | 54006-2 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520237 | Midbody Pattern | 54155-7 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520237 | |||||
Result Name | Midbody Pattern | |||||
UofM | ||||||
Result LOINC | 54155-7 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520238 | Nuclear Dot Pattern | 53998-1 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520238 | |||||
Result Name | Nuclear Dot Pattern | |||||
UofM | ||||||
Result LOINC | 53998-1 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520239 | PCNA Pattern | 53006-3 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520239 | |||||
Result Name | PCNA Pattern | |||||
UofM | ||||||
Result LOINC | 53006-3 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520240 | Centriole Pattern | 53993-2 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520240 | |||||
Result Name | Centriole Pattern | |||||
UofM | ||||||
Result LOINC | 53993-2 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520241 | Note: | 77202-0 | |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520241 | |||||
Result Name | Note: | |||||
UofM | ||||||
Result LOINC | 77202-0 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520218 | Anti-Ro (SS-A) Ab (RDL) | Units | 33569-5 |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520218 | |||||
Result Name | Anti-Ro (SS-A) Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 33569-5 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520225 | Anti-La (SS-B) Ab (RDL) | Units | 45142-7 |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520225 | |||||
Result Name | Anti-La (SS-B) Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 45142-7 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520216 | Anti-Sm Ab (RDL) | Units | 11090-8 |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520216 | |||||
Result Name | Anti-Sm Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 11090-8 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520217 | Anti-U1 RNP Ab (RDL) | Units | 57662-9 |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520217 | |||||
Result Name | Anti-U1 RNP Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 57662-9 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520289 | ILDDX Positive ANA | 520060 | Anti-dsDNA Ab by Farr(RDL) | IU/mL | 47299-3 |
Reflex 1 | ||||||
Order Code | 520289 | |||||
Order Name | ILDDX Positive ANA | |||||
Result Code | 520060 | |||||
Result Name | Anti-dsDNA Ab by Farr(RDL) | |||||
UofM | IU/mL | |||||
Result LOINC | 47299-3 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520288 | Positive ANCA Reflex | 520187 | C-ANCA (IFA-ETOH) | 14277-8 | |
Reflex 1 | ||||||
Order Code | 520288 | |||||
Order Name | Positive ANCA Reflex | |||||
Result Code | 520187 | |||||
Result Name | C-ANCA (IFA-ETOH) | |||||
UofM | ||||||
Result LOINC | 14277-8 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520288 | Positive ANCA Reflex | 520189 | P-ANCA (IFA-ETOH) | 14278-6 | |
Reflex 1 | ||||||
Order Code | 520288 | |||||
Order Name | Positive ANCA Reflex | |||||
Result Code | 520189 | |||||
Result Name | P-ANCA (IFA-ETOH) | |||||
UofM | ||||||
Result LOINC | 14278-6 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520288 | Positive ANCA Reflex | 520191 | P-ANCA (IFA-Formalin) | 17357-5 | |
Reflex 1 | ||||||
Order Code | 520288 | |||||
Order Name | Positive ANCA Reflex | |||||
Result Code | 520191 | |||||
Result Name | P-ANCA (IFA-Formalin) | |||||
UofM | ||||||
Result LOINC | 17357-5 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520288 | Positive ANCA Reflex | 520154 | Anti-MPO Ab (RDL) | Units | 72515-0 |
Reflex 1 | ||||||
Order Code | 520288 | |||||
Order Name | Positive ANCA Reflex | |||||
Result Code | 520154 | |||||
Result Name | Anti-MPO Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 72515-0 |
Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
---|---|---|---|---|---|---|
Reflex 1 | 520288 | Positive ANCA Reflex | 520155 | Anti-PR-3 Ab (RDL) | Units | 63311-5 |
Reflex 1 | ||||||
Order Code | 520288 | |||||
Order Name | Positive ANCA Reflex | |||||
Result Code | 520155 | |||||
Result Name | Anti-PR-3 Ab (RDL) | |||||
UofM | Units | |||||
Result LOINC | 63311-5 |