Test Details
Methodology
Enzyme-linked immunosorbent assay (ELISA), RIPA
Result Turnaround Time
14 - 21 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Anti-EJ Ab; Anti-Jo-1 Ab; Anti-Ku Ab; Anti-MDA5 Ab; Anti-OJ Ab; Anti-PL-7 Ab; Anti-PL-12 Ab; Anti-PM/Scl-100 Ab; Anti-SSA 52 Ab; Anti-SRP Ab
Use
Interstitial Lung Disease (ILD) can complicate several collagen vascular diseases including Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Sjogren's Syndrome, Systemic Lupus Erythematosis, Rheumatoid Arthritis, and ANCA-Associated Vasculitis. This profile is designed to identify an underlying autoimmune disorder, assist therapeutic decision-making and assess disease prognosis.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Serum
Volume
3 mL
Minimum Volume
2 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
Storage Instructions
Refrigerate.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520259 | Anti-Jo-1 Ab (RDL) | Units | 35333-4 |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520046 | Anti-PL-7 Ab (RDL) | 33772-5 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520049 | Anti-PL-12 Ab (RDL) | 33771-7 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520027 | Anti-EJ Ab (RDL) | 45149-2 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520029 | Anti-OJ Ab (RDL) | 45152-6 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520040 | Anti-SRP Ab (RDL) | 33921-8 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520251 | Anti-MDA-5 Ab (CADM-140)(RDL) | Units | 103691-2 |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520228 | Anti-PM/Scl-100 Ab (RDL) | Units | 31562-2 |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520031 | Anti-Ku Ab (RDL) | 18484-6 | |
| 520202 | Interstitial Lung Disease Prof | 97564-9 | 520253 | Anti-SS-A 52kD Ab, IgG (RDL) | Units | 70257-1 |
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520259 | |||||
| Result Code Name | Anti-Jo-1 Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 35333-4 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520046 | |||||
| Result Code Name | Anti-PL-7 Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33772-5 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520049 | |||||
| Result Code Name | Anti-PL-12 Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33771-7 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520027 | |||||
| Result Code Name | Anti-EJ Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 45149-2 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520029 | |||||
| Result Code Name | Anti-OJ Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 45152-6 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520040 | |||||
| Result Code Name | Anti-SRP Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33921-8 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520251 | |||||
| Result Code Name | Anti-MDA-5 Ab (CADM-140)(RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 103691-2 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520228 | |||||
| Result Code Name | Anti-PM/Scl-100 Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 31562-2 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520031 | |||||
| Result Code Name | Anti-Ku Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 18484-6 | |||||
| Order Code | 520202 | |||||
| Order Code Name | Interstitial Lung Disease Prof | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520253 | |||||
| Result Code Name | Anti-SS-A 52kD Ab, IgG (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 70257-1 |