Test Details
Methodology
RIPA gel radiography, Enzyme-linked immunosorbent assay (ELISA)
Result Turnaround Time
14 - 21 days
Use
This Anti-Synthetase Profile is comprised of Anti-Jo-1 Ab, Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab and Anti-OJ Ab. Anti-synthetase syndrome is an autoimmune disease characterized by interstitial lung disease (ILD), non-erosive arthritis, myositis, Raynaud’s phenomenon, unexplained fever and/or mechanic’s hands.1
Specimen Requirements
Test Includes
Anti-EJ Ab; Anti-Jo-1 Ab; Anti-OJ Ab; Anti-PL-7 Ab, Anti-PL-12 Ab
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520193 | Anti-Synthetase Profile (RDL) | 97564-9 | 520259 | Anti-Jo-1 Ab (RDL) | Units | 35333-4 |
| 520193 | Anti-Synthetase Profile (RDL) | 97564-9 | 520046 | Anti-PL-7 Ab (RDL) | 33772-5 | |
| 520193 | Anti-Synthetase Profile (RDL) | 97564-9 | 520049 | Anti-PL-12 Ab (RDL) | 33771-7 | |
| 520193 | Anti-Synthetase Profile (RDL) | 97564-9 | 520027 | Anti-EJ Ab (RDL) | 45149-2 | |
| 520193 | Anti-Synthetase Profile (RDL) | 97564-9 | 520029 | Anti-OJ Ab (RDL) | 45152-6 | |
| Order Code | 520193 | |||||
| Order Code Name | Anti-Synthetase Profile (RDL) | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520259 | |||||
| Result Code Name | Anti-Jo-1 Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 35333-4 | |||||
| Order Code | 520193 | |||||
| Order Code Name | Anti-Synthetase Profile (RDL) | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520046 | |||||
| Result Code Name | Anti-PL-7 Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33772-5 | |||||
| Order Code | 520193 | |||||
| Order Code Name | Anti-Synthetase Profile (RDL) | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520049 | |||||
| Result Code Name | Anti-PL-12 Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33771-7 | |||||
| Order Code | 520193 | |||||
| Order Code Name | Anti-Synthetase Profile (RDL) | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520027 | |||||
| Result Code Name | Anti-EJ Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 45149-2 | |||||
| Order Code | 520193 | |||||
| Order Code Name | Anti-Synthetase Profile (RDL) | |||||
| Order Loinc | 97564-9 | |||||
| Result Code | 520029 | |||||
| Result Code Name | Anti-OJ Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 45152-6 |