Test Details
Methodology
Enzyme-linked immunosorbent assay (ELISA); Indirect fluorescent antibody (IFA)
Result Turnaround Time
7 - 10 days
Use
C-ANCA & P-ANCA resulted if positive, otherwise reported as ANCA Negative. PANCA confirmed on formalin fixed slides. ANA performed if ANCA positive to rule out false positive ANCA due to presence of ANA.
Specimen Requirements
Test Includes
ANCA; Anti-MPO (Myeloperoxidase) Ab; Anti-PR-3 (Proteinase 3) Ab; c-ANCA ans p-ANCA are resulted if positive. Otherwise, ANCA is reported as negative. Anti-Nuclear Ab (ANA) by IFA is performed if ANCA positive.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen
Serum
Volume
3 mL
Minimum Volume
2 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520149 | ANCA Profile (RDL) | 520150 | ANCA by IFA (RDL) | 29641-8 | ||
| 520149 | ANCA Profile (RDL) | 520154 | Anti-MPO Ab (RDL) | Units | 72515-0 | |
| 520149 | ANCA Profile (RDL) | 520155 | Anti-PR-3 Ab (RDL) | Units | 63311-5 | |
| Order Code | 520149 | |||||
| Order Code Name | ANCA Profile (RDL) | |||||
| Order Loinc | ||||||
| Result Code | 520150 | |||||
| Result Code Name | ANCA by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 29641-8 | |||||
| Order Code | 520149 | |||||
| Order Code Name | ANCA Profile (RDL) | |||||
| Order Loinc | ||||||
| Result Code | 520154 | |||||
| Result Code Name | Anti-MPO Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 72515-0 | |||||
| Order Code | 520149 | |||||
| Order Code Name | ANCA Profile (RDL) | |||||
| Order Loinc | ||||||
| Result Code | 520155 | |||||
| Result Code Name | Anti-PR-3 Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 63311-5 |
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520187 | C-ANCA (IFA-ETOH) | 14277-8 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520187 | |||||
| Result Name | C-ANCA (IFA-ETOH) | |||||
| UofM | ||||||
| Result LOINC | 14277-8 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520189 | P-ANCA (IFA-ETOH) | 14278-6 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520189 | |||||
| Result Name | P-ANCA (IFA-ETOH) | |||||
| UofM | ||||||
| Result LOINC | 14278-6 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520191 | P-ANCA (IFA-Formalin) | 17357-5 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520191 | |||||
| Result Name | P-ANCA (IFA-Formalin) | |||||
| UofM | ||||||
| Result LOINC | 17357-5 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 520245 | Positive ANCA Reflex | 520073 | Anti-Nuclear Ab by IFA (RDL) | 42254-3 | |
| Reflex 1 | ||||||
| Order Code | 520245 | |||||
| Order Name | Positive ANCA Reflex | |||||
| Result Code | 520073 | |||||
| Result Name | Anti-Nuclear Ab by IFA (RDL) | |||||
| UofM | ||||||
| Result LOINC | 42254-3 | |||||