Test Details
Methodology
Enzyme-linked immunosorbent assay (ELISA)
Result Turnaround Time
5 - 7 days
Use
Anti-U1 RNP antibodies typically appear in both SLE and MCTD. In MCTD, the presence of U1 RNP is required for diagnosis, whereas anti-RNP antibodies occur in only 30-40% of SLE. MCTD is typified by the high-titer RNP antibody activity in isolation; anti-RNP antibody activity in SLE commonly accompanies anti-Sm antibodies.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520034 | Anti-U1 RNP Ab (RDL) | 53022-0 | 520035 | Anti-U1 RNP Ab (RDL) | Units | 53022-0 |
| Order Code | 520034 | |||||
| Order Code Name | Anti-U1 RNP Ab (RDL) | |||||
| Order Loinc | 53022-0 | |||||
| Result Code | 520035 | |||||
| Result Code Name | Anti-U1 RNP Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 53022-0 |