Test Details
Methodology
Enzyme immunoassay (EIA)
Result Turnaround Time
14 - 21 days
Use
PR-3 are an aid in the assessment of certain autoimmune vasculitides such as microscopic polyarteritis and crescentic glomerulonephritis. PR-3 is the major target antigen of antineutrophil cytoplasmic autoantibodies (ANCA) that give a cytoplasmic (C-ANCA) immunofluorescence pattern. Elevated levels of PR-3 autoantibodies are classically observed in patients with Wegener granulomatosis (WG), particularly with active disease, and less frequently in other forms of necrotizing vasculitis.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520023 | Anti-PR-3 Ab (RDL) | 46267-1 | 520050 | Anti-PR-3 Ab (RDL) | Units | 46267-1 |
| Order Code | 520023 | |||||
| Order Code Name | Anti-PR-3 Ab (RDL) | |||||
| Order Loinc | 46267-1 | |||||
| Result Code | 520050 | |||||
| Result Code Name | Anti-PR-3 Ab (RDL) | |||||
| UofM | Units | |||||
| Result LOINC | 46267-1 |