Test Details
Methodology
RIPA gel radiography
Result Turnaround Time
14 - 21 days
Use
Anti-histidyl-tRNA synthetase autoantibodies are the most common MSA, comprising 30-40% of Idiopathic Inflammatory Myopathies (IIM), although PL-12 specifically is seen in less than 5% of IIM. Anti-Synthetase antibodies can be found in polymyositis, dermatomyositis or overlap myositis. Symptoms associated with these antibodies include non-erosive arthritis, ILD, fever, mechanic's hands and Raynaud's.
Specimen Requirements
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 14 days |
Frozen | 60 days |
Freeze/thaw cycles | Stable x1 |
Reference Range
Negative
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 520006 | Anti-PL-12 Ab (RDL) | 33771-7 | 520049 | Anti-PL-12 Ab (RDL) | 33771-7 | |
| Order Code | 520006 | |||||
| Order Code Name | Anti-PL-12 Ab (RDL) | |||||
| Order Loinc | 33771-7 | |||||
| Result Code | 520049 | |||||
| Result Code Name | Anti-PL-12 Ab (RDL) | |||||
| UofM | ||||||
| Result LOINC | 33771-7 |