Test Details
Methodology
Fluorescence in situ hybridization (FISH)
Result Turnaround Time
2 - 3 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
This test is used for fluorescence in situ hybridization (FISH), prenatal chorionic villus sampling, and FISH targeting numerical changes in 13, 18, 21, X and Y.
Special Instructions
Pertinent medical findings should accompany request for FISH. It is required that InSight FISH testing be performed concurrently with prenatal chromosome analysis or microarray. Abnormal results should have banded chromosome confirmation.
Pertinent medical findings should accompany request for FISH. It is re |
Pertinent medical findings should accompany request for FISH. It is required that InSight FISH testing be performed concurrently with prenatal chromosome analysis or microarray. Abnormal results should have banded chromosome confirmation. |
Limitations
Molecular mutations below the resolution of FISH will not be detected; will not detect aneuploidy that is not targeted by FISH probes in this panel.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Chorionic villi
Volume
5 mg chorionic villi or greater
|
5 mg chorionic villi or greater |
Minimum Volume
5 mg chorionic villi (Note: Minimum volumes may not allow for repeat testing.)
Container
The CVS transport tube (a sterile specimen container with transport medium) is available from Labcorp. Please call customer service at 800-345-4363.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
No villi submitted in specimen; low volume; wrong specimen type; frozen specimen; specimen placed in fixative
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510803 | Cells Counted | 64089-6 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510804 | Cells Analyzed | 64086-2 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510805 | Cytogenetic Diagnosis | 57318-8 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510958 | Cytogenetic Interpretation | 62365-2 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510807 | Specimen Type | 31208-2 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 510959 | Director Review: | 72486-4 | |
| 510960 | FISH, CVS Prenatal Aneuploid | 57317-0 | 512123 | 11502-2 | ||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510803 | |||||
| Result Code Name | Cells Counted | |||||
| UofM | ||||||
| Result LOINC | 64089-6 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510804 | |||||
| Result Code Name | Cells Analyzed | |||||
| UofM | ||||||
| Result LOINC | 64086-2 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510805 | |||||
| Result Code Name | Cytogenetic Diagnosis | |||||
| UofM | ||||||
| Result LOINC | 57318-8 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510958 | |||||
| Result Code Name | Cytogenetic Interpretation | |||||
| UofM | ||||||
| Result LOINC | 62365-2 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510807 | |||||
| Result Code Name | Specimen Type | |||||
| UofM | ||||||
| Result LOINC | 31208-2 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 510959 | |||||
| Result Code Name | Director Review: | |||||
| UofM | ||||||
| Result LOINC | 72486-4 | |||||
| Order Code | 510960 | |||||
| Order Code Name | FISH, CVS Prenatal Aneuploid | |||||
| Order Loinc | 57317-0 | |||||
| Result Code | 512123 | |||||
| Result Code Name | ||||||
| UofM | ||||||
| Result LOINC | 11502-2 |