Test Details
Methodology
Nucleic acid amplification (NAA)
Result Turnaround Time
4 - 6 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Specifically identifies types HPV 16 and HPV 18 while concurrently detecting the rest of the high-risk types: 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without further specific differentiation.
Limitations
Detection of HPV is dependent on the number of copies present in the specimen and may be affected by specimen collection methods, patient factors, stage of infection, and the presence of interfering substances.
Specimen Requirements
Specimen
Rectal swab
Volume
2 mL
Minimum Volume
1 mL
Container
ThinPrep® vial only
Collection Instructions
An anal-rectal cytology specimen is collected using a Dacron swab (for example: AMD-Ritmed Company Catalog N° 4001D, LabCorp N° 19762). Moisten the swab in tap water and insert as far as possible into the anal canal. Slowly rotate the swab in one direction with gentle pressure on the walls as the swab is slowly being withdrawn. Care should be taken to ensure the transition zone is sampled. Vigorously rotate the swab in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the swab vigorously to release additional material. Discard the swab. Tighten the cap on the ThinPrep® container so that the torque line on the cap passes the torque line on the vial.
Storage Instructions
Room temperature
Causes for Rejection
Improper collection or inadequate specimen; improperly labeled; specimen more than six months old in ThinPrep® vial; frozen specimens; specimen leaked in transit; quantity not sufficient for analysis; name discrepancies; excessively bloody specimens.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 508005 | cobas HPV, Rectal | 77376-2 | 508006 | HPV other hr types | 77394-5 | |
| 508005 | cobas HPV, Rectal | 77376-2 | 508007 | HPV 16 | 77396-0 | |
| 508005 | cobas HPV, Rectal | 77376-2 | 508008 | HPV 18 | 77395-2 | |
| Order Code | 508005 | |||||
| Order Code Name | cobas HPV, Rectal | |||||
| Order Loinc | 77376-2 | |||||
| Result Code | 508006 | |||||
| Result Code Name | HPV other hr types | |||||
| UofM | ||||||
| Result LOINC | 77394-5 | |||||
| Order Code | 508005 | |||||
| Order Code Name | cobas HPV, Rectal | |||||
| Order Loinc | 77376-2 | |||||
| Result Code | 508007 | |||||
| Result Code Name | HPV 16 | |||||
| UofM | ||||||
| Result LOINC | 77396-0 | |||||
| Order Code | 508005 | |||||
| Order Code Name | cobas HPV, Rectal | |||||
| Order Loinc | 77376-2 | |||||
| Result Code | 508008 | |||||
| Result Code Name | HPV 18 | |||||
| UofM | ||||||
| Result LOINC | 77395-2 |