Autoimmune Myelopathy Profile

CPT: 84182; 86051; 86255(x15); 86341; 86362
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Expected Turnaround Time

5 - 7 days


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Specimen Requirements


Specimen

Serum (gel barrier tube or red-top tube)


Volume

2 mL


Minimum Volume

1 mL (Note: This volume does not allow for repeat testing.)


Container

Gel barrier tube, serum transfer tube


Stability Requirements

TemperaturePeriod
Room temperature14 days
Refrigerated14 days
Frozen14 days
Freeze/thaw cyclesStable x3

Causes for Rejection

Gross hemolysis; grossly lipemic; gross icetrus


Test Details


Use

This test can assist in the diagnosis (paraneoplastic or idiopathic autoimmune) and aid distinction from other causes of myelopathy (sarcoidosis, vascular disease, multiple sclerosis). Early testing may assist in early diagnosis of occult cancer, prompt initiation of immune therapies, or both.


Limitations

This test was developed and its performance characteristics determined by Labcorp in accordance with CLIA requirements. This test has not been cleared or approved by the Food and Drug Administration.


Methodology

Immunofluorescence, EIA, Immunoblot


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
505592 Autoimmune Myelopathy Ab 000000
505592 Autoimmune Myelopathy Ab 505241 Anti-Hu Ab 49738-8
505592 Autoimmune Myelopathy Ab 505243 Anti-Ri Ab 43187-4
505592 Autoimmune Myelopathy Ab 505245 PCA Type-1 (Anti-Yo) Ab 84924-0
505592 Autoimmune Myelopathy Ab 505311 MOG Antibody, Cell-based IFA 91545-4
505592 Autoimmune Myelopathy Ab 505469 Antineuronal nuclear Ab Type 3 43102-3
505592 Autoimmune Myelopathy Ab 505470 Amphiphysin Antibody 33422-7
505592 Autoimmune Myelopathy Ab 505471 Purkinje Cell Cyto Ab Type 2 84925-7
505592 Autoimmune Myelopathy Ab 505472 Purkinje Cell Cyto Ab Type Tr 84926-5
505592 Autoimmune Myelopathy Ab 505486 CRMP-5 IgG 43103-1
505592 Autoimmune Myelopathy Ab 505487 CRMP-5 IgG Line Blot 47401-5
505592 Autoimmune Myelopathy Ab 505488 AGNA-1 84927-3
505592 Autoimmune Myelopathy Ab 505491 DPPX Antibody 82976-2
505592 Autoimmune Myelopathy Ab 505492 mGluR1 Antibody 94347-2
505592 Autoimmune Myelopathy Ab 505519 AMPA-R1 Antibody 84929-9
505592 Autoimmune Myelopathy Ab 505524 AMPA-R2 Antibody 84930-7
505592 Autoimmune Myelopathy Ab 505534 GABA-B-R Antibody 84931-5
505592 Autoimmune Myelopathy Ab 505536 NMDA-R Antibody 84928-1
505592 Autoimmune Myelopathy Ab 505537 GAD65 Antibody 94345-6
505592 Autoimmune Myelopathy Ab 505547 Aquaporin 4 Antibody 61430-5
505592 Autoimmune Myelopathy Ab 505548 Interpretation 56850-1

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf