Find Locations
For hours, walk-ins and appointments.Synonyms
- Vectra® DA Disease Activity Test
- Vectra® Score
- Vectra® Disease Activity
- MBDA
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Expected Turnaround Time
6 - 8 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
For more information, please view the literature below.
Vectra Post-Test Patient Brochure
Vectra Post-Test Patient Brochure — Spanish
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For more information, please view the literature below. |
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For more information, please view the literature below. Vectra Post-Test Patient Brochure Vectra Post-Test Patient Brochure — Spanish |
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection
Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.
Storage Instructions
Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 3 days |
| Refrigerated | 14 days |
| Frozen | 326 days |
Causes for Rejection
Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old
Test Details
Use
Vectra® measures 12 biomarkers and incorporates age, gender and adiposity in adult
patients with rheumatoid arthritis (RA) to provide a single score that is an objective measure of
inflammation, which reflects disease activity, predicts risk of radiographic progression and
informs medical management decisions designed to prevent irreversible joint damage. The 12
biomarkers required to generate a Vectra® Score are VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP1,
MMP3, YKL-40, Leptin, Resistin, SAA and CRP.
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Vectra® DA measures the concentration of 12 serum proteins. An algorithm is applied to these concentrations to calculate a quantitate disease activity score ranging from 1 to 100. Test results are intended to aid in the assessment of disease activity in RA patients when used in conjunction with standard clinical assessment. This test is not intended or validated to diagnose RA. An order for Vectra® DA includes and requires an order for 12 biomarkers: VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP-1, YKL-40, Leptin, Resistin, SAA, CRP. These 12 biomarkers are required to generate the Vectra® DA test score. By ordering Vectra® DA, you are ordering all 12 biomarkers and are acknowledging that Labcorp cannot provide a Vectra® DA test result without these 12 biomarkers. Vectra® DA was validated in adults with Rheumatoid Arthritis (RA). |
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Vectra® measures 12 biomarkers and incorporates age, gender and adiposity in adultpatients with rheumatoid arthritis (RA) to provide a single score that is an objective measure ofinflammation, which reflects disease activity, predicts risk of radiographic progression andinforms medical management decisions designed to prevent irreversible joint damage. The 12biomarkers required to generate a Vectra® Score are VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP1,MMP3, YKL-40, Leptin, Resistin, SAA and CRP. |
Methodology
Multiplex bead-based immunoassay and Meso Scale Discovery Multi-array Platform
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