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Vectra®

CPT

81490

Synonyms
  • Vectra® DA Disease Activity Test
  • Vectra® Score
  • Vectra® Disease Activity
  • MBDA

Test Details

Methodology

Multiplex bead-based immunoassay and Meso Scale Discovery Multi-array Platform

Result Turnaround Time

6 - 8 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

Vectra® measures 12 biomarkers and incorporates age, gender and adiposity in adult
patients with rheumatoid arthritis (RA) to provide a single score that is an objective measure of
inflammation, which reflects disease activity, predicts risk of radiographic progression and
informs medical management decisions designed to prevent irreversible joint damage. The 12
biomarkers required to generate a Vectra® Score are VCAM-1, EGF, VEGF-A, IL-6, TNF-RI, MMP1,
MMP3, YKL-40, Leptin, Resistin, SAA and CRP.

Specimen Requirements

Specimen

Serum

Volume

2 mL

Minimum Volume

1 mL

Container

Gel-barrier tube, red-top tube or serum transfer tube

Collection Instructions

Allow specimen to clot for 30 minutes. Centrifuge and separate from cells within 45 minutes of draw. Transfer to a plastic transport tube before shipping.

Stability Requirements

TemperaturePeriod
Room temperature3 days
Refrigerated14 days
Frozen326 days

Storage Instructions

Ship on frozen cool packs or dry ice. Ship with enough dry ice so ice exists upon receipt of package. Samples cannot go above room temperature.

Causes for Rejection

Gross hemolysis; gross lipemia; improper labeling; patients less than 18 years old or more than 100 years old

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
504965 Vectra(R) 75635-3 504966 Vectra Score 75633-8
504965 Vectra(R) 75635-3 504967 Risk of Radiographic Progress % N/A
504965 Vectra(R) 75635-3 504969 Vectra(R) Level 75634-6
504965 Vectra(R) 75635-3 504968 Test Description N/A
504965 Vectra(R) 75635-3 504973 SAA Result ug/mL 1847-3
504965 Vectra(R) 75635-3 504974 CRP Result mg/L 1988-5
504965 Vectra(R) 75635-3 504975 VCAM-1 Result ug/mL 75627-0
504965 Vectra(R) 75635-3 504976 IL-6 Result pg/mL 26881-3
504965 Vectra(R) 75635-3 504977 TNF-RI Result ng/mL 75629-6
504965 Vectra(R) 75635-3 504978 EGF Result pg/mL 14049-1
504965 Vectra(R) 75635-3 504979 VEGF-A Result pg/mL 75628-8
504965 Vectra(R) 75635-3 504981 Leptin Result ng/mL 21365-2
504965 Vectra(R) 75635-3 504982 Resistin Result ng/mL 75632-0
504965 Vectra(R) 75635-3 504983 MMP-1 Result ng/mL 75630-4
504965 Vectra(R) 75635-3 504984 MMP3 Result ng/mL 75631-2
504965 Vectra(R) 75635-3 504985 YKL-40 Result ng/mL 48663-9
504965 Vectra(R) 75635-3 504999 Biomarker Comment: N/A
504965 Vectra(R) 75635-3 504986 Footnote/History N/A
504965 Vectra(R) 75635-3 504970 Clinical Validation N/A
504965 Vectra(R) 75635-3 504997 Vectra(R) PDF 11502-2
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504966
Result Code NameVectra Score
UofM
Result LOINC75633-8
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504967
Result Code NameRisk of Radiographic Progress
UofM%
Result LOINCN/A
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504969
Result Code NameVectra(R) Level
UofM
Result LOINC75634-6
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504968
Result Code NameTest Description
UofM
Result LOINCN/A
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504973
Result Code NameSAA Result
UofMug/mL
Result LOINC1847-3
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504974
Result Code NameCRP Result
UofMmg/L
Result LOINC1988-5
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504975
Result Code NameVCAM-1 Result
UofMug/mL
Result LOINC75627-0
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504976
Result Code NameIL-6 Result
UofMpg/mL
Result LOINC26881-3
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504977
Result Code NameTNF-RI Result
UofMng/mL
Result LOINC75629-6
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504978
Result Code NameEGF Result
UofMpg/mL
Result LOINC14049-1
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504979
Result Code NameVEGF-A Result
UofMpg/mL
Result LOINC75628-8
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504981
Result Code NameLeptin Result
UofMng/mL
Result LOINC21365-2
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504982
Result Code NameResistin Result
UofMng/mL
Result LOINC75632-0
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504983
Result Code NameMMP-1 Result
UofMng/mL
Result LOINC75630-4
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504984
Result Code NameMMP3 Result
UofMng/mL
Result LOINC75631-2
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504985
Result Code NameYKL-40 Result
UofMng/mL
Result LOINC48663-9
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504999
Result Code NameBiomarker Comment:
UofM
Result LOINCN/A
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504986
Result Code NameFootnote/History
UofM
Result LOINCN/A
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504970
Result Code NameClinical Validation
UofM
Result LOINCN/A
Order Code504965
Order Code NameVectra(R)
Order Loinc75635-3
Result Code504997
Result Code NameVectra(R) PDF
UofM
Result LOINC11502-2