Find Locations
For hours, walk-ins and appointments.Recurrent Miscarriage/Fetal Demise Profile (Esoterix)
CPT:
81240; 81241; 83090; 85290; 85300; 85303; 85306; 85415; 85598; 85613(x2); 85730; 85732(x2); 86146(x3); 86147(x3); 86148(x2)
Synonyms
- Obstetric Complications Profile
Test Includes
Activated partial thromboplastin time (aPTT); anticardiolipin antibodies IgA, IgG, IgM; antiphosphatidylserine, IgG, IgM; antithrombin activity; APTT mixing studies; β2-glycoprotein I, IgA, IgG, IgM; dRVVT; factor II gene mutation; factor V Leiden; factor XIII activity; hexagonal phospholipid neutralization; homocysteine; lupus anticoagulant interpretation; plasminogen activator inhibitor-1 (PAI-1) activity; protein C activity (chromogenic); protein S antigen, free
Special Instructions
Informed consent is required for New York patients. If abnormal, aPTT will reflex to immediate aPTT mixing studies. If reflex test is performed, additional charges/CPT code(s) may apply.
Expected Turnaround Time
5 - 9 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Specimen Requirements
Specimen
Serum, plasma, and whole blood
Volume
Five 1-mL tubes of platelet-poor frozen citrated plasma and 5 mL whole blood and 2 mL frozen serum
Container
Blue-top (sodium citrate) tube citrated platelet-free plasma and lavender-top (EDTA) tube or yellow-top (ACD) tube and red-top tube or gel-barrier tube.
Collection
Plasma/serum must be separated from cells within 45 minutes of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed.
Storage Instructions
Freeze plasma or serum. Maintain whole blood at room temperature; stable for seven days.
Causes for Rejection
Noncitrated plasma; gross homolysis; presence of fibrin; clotted plasma; clotted whole blood samples if adequate DNA not obtained; frozen whole blood
Test Details
Limitations
This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.
Methodology
See individual tests.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 502051 | OB Complications Profile | 501701 | Homocysteine | umol/L | 13965-9 | |
| 502051 | OB Complications Profile | 500186 | Factor XIII Activity** | % | 27815-0 | |
| 502051 | OB Complications Profile | 500616 | PAI-1 Activity | IU/mL | 5975-8 | |
| 502051 | OB Complications Profile | 500573 | Antithrombin Activity, Plasma | % | 27811-9 | |
| 502051 | OB Complications Profile | 500464 | Prt C Activity (Chromogenic) | % | 27818-4 | |
| 502051 | OB Complications Profile | 500618 | Protein S Antigen, Free | % | 27821-8 | |
| 502051 | OB Complications Profile | 500513 | APTT | sec | 14979-9 | |
| 502051 | OB Complications Profile | 500363 | APTT 1:1 NP | sec | 5946-9 | |
| 502051 | OB Complications Profile | 500364 | APTT 1:1 Saline | Sec | 43734-3 | |
| 502051 | OB Complications Profile | 501549 | DRVVT Screen Seconds | sec | 6303-2 | |
| 502051 | OB Complications Profile | 501548 | DRVVT Confirm Seconds | sec | 57838-5 | |
| 502051 | OB Complications Profile | 500585 | DRVVT Ratio | ratio | 50410-0 | |
| 502051 | OB Complications Profile | 500569 | Hexagonal Phospholipid Neutral | sec | 3282-1 | |
| 502051 | OB Complications Profile | 500575 | Anticardiolipin Ab, IgG | GPL | 3181-5 | |
| 502051 | OB Complications Profile | 500571 | Anticardiolipin Ab, IgM | MPL | 3182-3 | |
| 502051 | OB Complications Profile | 500581 | Anticardiolipin Ab, IgA | APL | 5076-5 | |
| 502051 | OB Complications Profile | 500589 | Beta-2 Glycoprotein I, IgG | SGU | 16135-6 | |
| 502051 | OB Complications Profile | 500593 | Beta-2 Glycoprotein I, IgM | SMU | 16136-4 | |
| 502051 | OB Complications Profile | 500591 | Beta-2 Glycoprotein I, IgA | SAU | 21108-6 | |
| 502051 | OB Complications Profile | 500577 | Antiphosphatidylserine IgG | GPS | 32032-5 | |
| 502051 | OB Complications Profile | 500579 | Antiphosphatidylserine IgM | MPS | 32033-3 | |
| 502051 | OB Complications Profile | 502038 | LAC Interpretation | 77202-0 | ||
| 502051 | OB Complications Profile | 500587 | Factor V Leiden Result | 21667-1 | ||
| 502051 | OB Complications Profile | 500627 | Interpretation: | 51968-6 | ||
| 502051 | OB Complications Profile | 500628 | Methodology: | 49549-9 | ||
| 502051 | OB Complications Profile | 500629 | Comments: | 77202-0 | ||
| 502051 | OB Complications Profile | 500583 | Factor II Gene Mutation Result | 24476-4 | ||
| 502051 | OB Complications Profile | 500624 | Interpretation: | 51968-6 | ||
| 502051 | OB Complications Profile | 500625 | Methodology: | 49549-9 | ||
| 502051 | OB Complications Profile | 500626 | Comments: | 77202-0 |
© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.
CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf