Test Details
Methodology
Immunochemiluminometric (ICMA) or double antibody radioimmunoassay (RIA) when anti-Tg autoantibodies are present
Result Turnaround Time
4 - 10 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Comprehensive thyroglobulin can be used to monitor recurrence of thyroid cancer. All specimens are tested for the presence of antithyroglobulin autoantibodies (anti-Tg). Specimens negative for the presence of anti-Tg are reflexed to thyroglobulin testing by ICMA, and specimens positive for the presence of anti-Tg are reflexed to thyroglobulin testing by RIA.
Specimens submitted for comprehensive thyroglobulin testing are stored frozen for one year to allow for future testing.
Specimen Requirements
Specimen
Serum
Volume
5 mL
Minimum Volume
1.5 mL (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube or red-top tube
Collection Instructions
Transfer specimen to a plastic transport tube before freezing. Serum must be separated from cells within one hour of venipuncture. Submit serum in a plastic transport tube.
Storage Instructions
Freeze. Stable at room temperature for three days or refrigerated for 14 days. Stable when frozen for 3.79 years. Freeze/thaw cycles: stable x2.
Causes for Rejection
Plasma specimen received; gross hemolysis
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 500540 | Comprehensive Thyroglobulin | 57780-9 | 500556 | Anti-Thyroglobulin Antibodies | IU/mL | 8098-6 |
| 500540 | Comprehensive Thyroglobulin | 57780-9 | 503191 | Thyroglobulin (ICMA) | ng/mL | 3013-0 |
| 500540 | Comprehensive Thyroglobulin | 57780-9 | 500002 | Thyroglobulin (TG-RIA) | ng/mL | 3013-0 |
| Order Code | 500540 | |||||
| Order Code Name | Comprehensive Thyroglobulin | |||||
| Order Loinc | 57780-9 | |||||
| Result Code | 500556 | |||||
| Result Code Name | Anti-Thyroglobulin Antibodies | |||||
| UofM | IU/mL | |||||
| Result LOINC | 8098-6 | |||||
| Order Code | 500540 | |||||
| Order Code Name | Comprehensive Thyroglobulin | |||||
| Order Loinc | 57780-9 | |||||
| Result Code | 503191 | |||||
| Result Code Name | Thyroglobulin (ICMA) | |||||
| UofM | ng/mL | |||||
| Result LOINC | 3013-0 | |||||
| Order Code | 500540 | |||||
| Order Code Name | Comprehensive Thyroglobulin | |||||
| Order Loinc | 57780-9 | |||||
| Result Code | 500002 | |||||
| Result Code Name | Thyroglobulin (TG-RIA) | |||||
| UofM | ng/mL | |||||
| Result LOINC | 3013-0 |