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Anti-Müllerian Hormone (AMH) (Endocrine Sciences)

CPT 82166
Synonyms
  • Müllerian-inhibiting Substance

Test Details

Methodology

Electrochemiluminescence (ECL)

Result Turnaround Time

4 - 10 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

Anti-Müllerian Hormone Assay

References

American College of Obstetricians and Gynecologists. Committee on Gynecologic Practice. Committee Opinion N° 618: Ovarian reserve testing. Obstet Gynecol. 2015 Jan; 125(1):268-273. 25560143
Broer SL, Broekmans FJ, Laven JS, Fauser BC. Anti-Müllerian hormone: Ovarian reserve testing and its potential clinical implications. Hum Reprod Update. 2014 Sep-Oct; 20(5):688-701. 24821925
Fleming R, Broekmans F, Calhaz-Jorge C, et. al. Can anti-Müllerian hormone concentrations be used to determine gonadotrophin dose and treatment protocol for ovarian stimulation? Reprod Biomed Online. 2013 May; 26(5):431-439. 23507133
Gleicher N, Weghofer A, Barad DH. Anti-Müllerian hormone (AMH) defines, independent of age, low versus good live-birth chances in women with severely diminished ovarian reserve. Fertil Steril. 2010 Dec; 94(7): 2824-2827. 20538269
Karkanaki A, Vosnakis C, Panidis D. The clinical significance of anti-Mullerian hormone evaluation in gynecological endocrinology. Hormones (Athens). 2011 Apr-Jun; 10(2): 95-103. 21724534
La Marca A, Broekmans FJ, Volpe A, Fauser BC, Macklon NS; ESHRE Special Interest Group for Reproductive Endocrinology—AMH Round Table. Anti-Müllerian hormone (AMH): What do we still need to know? Hum Reprod. 2009 Sep; 24(9):2264-2275. 19520713
La Marca A, Sighinolfi G, Radi D, et al. Anti-Müllerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART). Hum Reprod Update. 2010 Mar-Apr; 16(2):113-130. 19793843
Ledger WL. Clinical utility of measurement of anti-Müllerian hormone in reproductive endocrinology. J Clin Endocrinol Metab. 2010 Dec; 95(12):5144-5154. 21131535
van Disseldorp J, Faddy MJ, Themmen APN, et al. Relationship of serum antimüllerian hormone concentration to age at menopause. J Clin Endocrinol Metab. 2008 Jun; 93(6):2129-2134. 18334591
van Rooij IA, Broekmans FJ, Scheffer GJ, et al. Serum antimüllerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: A longitudinal study. Fertil Steril. 2005; 83(4):979-987. 15820810

Specimen Requirements

Specimen

Serum, frozen

Volume

1 mL

Minimum Volume

0.2 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Collection Instructions

Transfer specimen to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Stability Requirements

Temperature

Period

Room temperature

1 day

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x6

Reference Range

See table.

Age

Range (ng/mL)

Median (ng/mL)

Male

Birth to 6 y

32.77−262.69

124.58

7 to 10 y

45.26−191.34

92.52

20 to 98 y

0.11−13.07

4.95

Female

0 to 6 y

0.53−7.78

2.85

7 to 19 y

1.05−12.86

5.23

20 to 25 y

1.23−11.51

4.70

26 to 30 y

1.03−11.10

4.20

31 to 35 y

0.66−8.75

3.00

36 to 40 y

0.42−8.34

1.69

41 to 46 y

0.26−5.81

0.58

47 to 54 y

≤0.82

<0.03

55 to 97 y

≤0.18

<0.03

Storage Instructions

Freeze.

Causes for Rejection

Gross hemolysis; gross lipemia; specimen at room temperature

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
500183 Anti-Mullerian Hormone (AMH) 38476-8 500184 Anti-Mullerian Hormone (AMH) ng/mL 38476-8
Order Code500183
Order Code NameAnti-Mullerian Hormone (AMH)
Order Loinc38476-8
Result Code500184
Result Code NameAnti-Mullerian Hormone (AMH)
UofMng/mL
Result LOINC38476-8