Test Details
Methodology
High-pressure liquid chromatography (HPLC) with tandem mass spectrometry
Result Turnaround Time
5 - 10 days
Use
Dihydrotestosterone and dihydrotestosterone/ratio may be used for differential diagnosis of diseases of sexual differentiation (DSD). DHT levels may be inappropriately low compared to testosterone levels in 5a-reductase deficiency. It is recommended by guidelines to measure the ratio of testosterone to DHT.
DHT levels may also be monitored to follow the effectiveness of 5a-reductase inhibitor treatment in female alopecia.
Specimen Requirements
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
References
Specimen
Serum (preferred) or plasma, frozen
Volume
1 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube
Storage Instructions
Freeze
Collection Instructions
Separate serum or plasma from cells within one hour of collection. Send serum or plasma in plastic transport tube. Transfer specimen to a plastic transport tube before freezing. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days |
Refrigerated | 7 days |
Frozen | 19 months |
Freeze/thaw cycles | Stable x6 |
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 500142 | Dihydrotestosterone | 1848-1 | 500143 | Dihydrotestosterone | ng/dL | 1848-1 |
| Order Code | 500142 | |||||
| Order Code Name | Dihydrotestosterone | |||||
| Order Loinc | 1848-1 | |||||
| Result Code | 500143 | |||||
| Result Code Name | Dihydrotestosterone | |||||
| UofM | ng/dL | |||||
| Result LOINC | 1848-1 |