Test Details
Methodology
Roche Diagnostics Electrochemiluminescence Immunoassay (ECLIA)
Result Turnaround Time
1 - 3 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Glial Fibrillary Acid Protein, Serum; GFAP, Serum Z Score; Neurofilament Light Chain, Serum; NFL, Serum Z Score
Use
This test is used to monitor Neurofilament Light Chain, Serum (NfL) and Glial Fibrillary Acid Protein, Serum (GFAP) values in multiple sclerosis patients.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Container
Gel-barrier tube (preferred) or red-top tube
Collection Instructions
If a red-top tube is used, transfer separated serum to a plastic transport tube.
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycle | Stable x3 |
Storage Instructions
Room temperature
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 484495 | MS Monitoring Profile | 484431 | Glial Fibrillary Acid Protein | pg/mL | 100435-7 | |
| 484495 | MS Monitoring Profile | 484432 | GFAP, Serum Z Score | pg/mL | Pending | |
| 484495 | MS Monitoring Profile | 140456 | Neurofilament Light Chain | pg/mL | 101281-4 | |
| 484495 | MS Monitoring Profile | 140457 | NFL, Serum Z Score | pg/mL | Pending | |
| 484495 | MS Monitoring Profile | 140796 | Comment | N/A | ||
| Order Code | 484495 | |||||
| Order Code Name | MS Monitoring Profile | |||||
| Order Loinc | ||||||
| Result Code | 484431 | |||||
| Result Code Name | Glial Fibrillary Acid Protein | |||||
| UofM | pg/mL | |||||
| Result LOINC | 100435-7 | |||||
| Order Code | 484495 | |||||
| Order Code Name | MS Monitoring Profile | |||||
| Order Loinc | ||||||
| Result Code | 484432 | |||||
| Result Code Name | GFAP, Serum Z Score | |||||
| UofM | pg/mL | |||||
| Result LOINC | Pending | |||||
| Order Code | 484495 | |||||
| Order Code Name | MS Monitoring Profile | |||||
| Order Loinc | ||||||
| Result Code | 140456 | |||||
| Result Code Name | Neurofilament Light Chain | |||||
| UofM | pg/mL | |||||
| Result LOINC | 101281-4 | |||||
| Order Code | 484495 | |||||
| Order Code Name | MS Monitoring Profile | |||||
| Order Loinc | ||||||
| Result Code | 140457 | |||||
| Result Code Name | NFL, Serum Z Score | |||||
| UofM | pg/mL | |||||
| Result LOINC | Pending | |||||
| Order Code | 484495 | |||||
| Order Code Name | MS Monitoring Profile | |||||
| Order Loinc | ||||||
| Result Code | 140796 | |||||
| Result Code Name | Comment | |||||
| UofM | ||||||
| Result LOINC | N/A |