Test Details
Methodology
Immunochemiluminometric (ICMA)
Result Turnaround Time
5 days
Use
This test is used for the quantitative measure of HER-2/neu in human serum. HER-2/neu values obtained may be used in the follow-up and monitoring of patients with metastatic breast cancer. HER-2/neu values should be used in conjunction with information available from clinical and other diagnostic procedures in the management of breast cancer. The clinical utility of the measurement of HER-2/neu as a prognostic indicator for early recurrence and in the management of patients on immunotherapy regimens has not been fully established.
Specimen Requirements
Limitations
Elevated levels of serum HER-2/neu are observed in a subset of patients with HER-2/neu-positive tumors. Approximately 25% to 30% of breast cancers demonstrate overexpression of the HER-2/neu protein.
References
Specimen
Serum, frozen
Volume
1 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Freeze
Causes for Rejection
Hemolysis; defrosted or freeze-thawed specimen
Collection Instructions
Transfer serum to screw-cap tube for shipping. Freeze specimen at -20°C and ship on dry ice. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 480136 | HER-2/neu, Serum | 480134 | Her-2/neu, Serum | ng/mL | 42914-2 | |
| 480136 | HER-2/neu, Serum | 511958 | 80563-0 | |||
| Order Code | 480136 | |||||
| Order Code Name | HER-2/neu, Serum | |||||
| Order Loinc | ||||||
| Result Code | 480134 | |||||
| Result Code Name | Her-2/neu, Serum | |||||
| UofM | ng/mL | |||||
| Result LOINC | 42914-2 | |||||
| Order Code | 480136 | |||||
| Order Code Name | HER-2/neu, Serum | |||||
| Order Loinc | ||||||
| Result Code | 511958 | |||||
| Result Code Name | ||||||
| UofM | ||||||
| Result LOINC | 80563-0 |