Test Details
Methodology
Next-generation sequencing or other methods as needed
Result Turnaround Time
3 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
HLA DQB1*06:02 and HLA DQA1*01:02 are associated statistically with narcolepsy and are sometimes used as tests in support of that diagnosis.
Special Instructions
This test currently is not approved for use in New York state.
If you have questions, please call HLA customer service at 800-533-1037 for assistance in selecting the appropriate HLA test for the patient.
Ship the specimen to arrive in the laboratory between Monday and Friday.
|
This test currently is not approved for use in New York state. If you have questions, please call HLA customer service at 800-533-1037 for assistance in selecting the appropriate HLA test for the patient. Ship the specimen to arrive in the laboratory between Monday and Friday. |
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Whole blood or buccal swabs
Volume
7 mL or four buccal swabs
Minimum Volume
3 mL or four buccal swabs
Container
Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). If submitting buccal swabs, please use the kit provided by Labcorp. To obtain the buccal swab kit or to discuss other specimen types, please call 800-533-1037.
Collection Instructions
Standard phlebotomy procedures or follow buccal swab kit instructions
Storage Instructions
Maintain specimen at room temperature. Protect from extreme heat or cold.
Causes for Rejection
Improper collection tube; mislabeled specimen
References
Mignot E, Lin L, Rogers W, et al. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. Am J Hum Genet. 2001 Mar;68(3):686-699. PubMed 11179016
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 167655 | Narcolepsy Evaluation | 94492-6 | 167656 | DQA1*01:02 | 53737-3 | |
| 167655 | Narcolepsy Evaluation | 94492-6 | 167657 | DQB1*06:02 | 63558-1 | |
| 167655 | Narcolepsy Evaluation | 94492-6 | 167149 | Please Note: | 77202-0 | |
| 167655 | Narcolepsy Evaluation | 94492-6 | 167135 | HLA NGS Methodology | 49549-9 | |
| Order Code | 167655 | |||||
| Order Code Name | Narcolepsy Evaluation | |||||
| Order Loinc | 94492-6 | |||||
| Result Code | 167656 | |||||
| Result Code Name | DQA1*01:02 | |||||
| UofM | ||||||
| Result LOINC | 53737-3 | |||||
| Order Code | 167655 | |||||
| Order Code Name | Narcolepsy Evaluation | |||||
| Order Loinc | 94492-6 | |||||
| Result Code | 167657 | |||||
| Result Code Name | DQB1*06:02 | |||||
| UofM | ||||||
| Result LOINC | 63558-1 | |||||
| Order Code | 167655 | |||||
| Order Code Name | Narcolepsy Evaluation | |||||
| Order Loinc | 94492-6 | |||||
| Result Code | 167149 | |||||
| Result Code Name | Please Note: | |||||
| UofM | ||||||
| Result LOINC | 77202-0 | |||||
| Order Code | 167655 | |||||
| Order Code Name | Narcolepsy Evaluation | |||||
| Order Loinc | 94492-6 | |||||
| Result Code | 167135 | |||||
| Result Code Name | HLA NGS Methodology | |||||
| UofM | ||||||
| Result LOINC | 49549-9 |