Test Details
Methodology
Immunologic
Result Turnaround Time
1 - 2 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
LDL and its major protein, apolipoprotein B, play an essential role in lipid transport and metabolism. Apo B may regulate cholesterol synthesis through its interaction with specific cell membrane receptors and by inhibition of HMG Co A reductase. This enzyme has been identified as the rate controlling enzyme in cholesterol biosynthesis. Apo B may be important in the genesis of atherosclerosis and its quantitation useful in the evaluation of patients at risk for or having coronary atherosclerosis (CAD). High levels indicate increased risk for CAD.
References
Specimen Requirements
Specimen
Serum (preferred) or plasma
Volume
2 mL
Container
Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection Instructions
Separate serum or plasma from cells. Transfer specimen to a plastic transport tube.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
Apolipoprotein B (mg/dL) | |||
|---|---|---|---|
Desirable | Borderline High | High | Very High |
<90 | 90 – 99 | 100 – 130 | >130 |
ASCVD Risk Category | Therapeutic Target APO B (mg/dL) |
|---|---|
Very High Risk | <80 (if extreme risk <70) |
High Risk | <90 |
Moderate Risk | <90 |
Storage Instructions
Maintain specimen at room temperature.
Patient Preparation
Patient must be fasting 12 to 14 hours.
Causes for Rejection
Specimen from nonfasting patient
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 167015 | Apolipoprotein B | 1884-6 | 167015 | Apolipoprotein B | mg/dL | 1884-6 |
| Order Code | 167015 | |||||
| Order Code Name | Apolipoprotein B | |||||
| Order Loinc | 1884-6 | |||||
| Result Code | 167015 | |||||
| Result Code Name | Apolipoprotein B | |||||
| UofM | mg/dL | |||||
| Result LOINC | 1884-6 |