Mycoplasma pneumoniae Antibodies, IgM

CPT: 86738
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Synonyms

  • Atypical Pneumonia Antibodies
  • Pleuropneumonia-like Organism (PPLO) Antibodies

Expected Turnaround Time

1 - 4 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.5 mL


Container

Red-top tube or gel-barrier tube


Storage Instructions

Maintain specimen at room temperature.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination


Test Details


Use

Aid in the diagnosis of atypical pneumonia and Stevens-Johnson syndrome by providing laboratory support for a Mycoplasma pneumoniae infection. Results must be interpreted in light of each patient's history, physical examination, and other diagnostic findings.


Limitations

The absorbent used in this assay removes as much as 15 mg/mL of human IgG, but the presence of residual IgG in individuals with hypergammaglobulinemia may affect results adversely.


Methodology

Enzyme immunoassay (EIA)


Reference Interval

Negative: <770 units/mL


Additional Information

Low positive results (770-950 units/mL) are presumptive evidence of acute or recent infection. It is recommended that the test be repeated on a fresh specimen one to two weeks later to assure reactivity. Specific IgM may persist for several months after initial infection or be absent during reinfection.


References

Ali NJ, Sillis M, Andrews BE, Jenkins PF, Harrison BD. The clinical spectrum and diagnosis of Mycoplasma pneumoniae infection. Q J Med. 1986 Mar; 58(227):241-251. 3737868
Levy M, Shear NH. Mycoplasma pneumoniae infections and Stevens-Johnson syndrome: Report of eight cases and review of the literature. Clin Pediatr (Phila). 1991 Jan; 30(1):42-49 (review). 1899814

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
163212 Mycoplasma pneumoniae, IgM Ab 5256-3 163213 M pneumoniae IgM Abs U/mL 5256-3

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