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Bartonella Antibody Profile

CPT 86611(x4)
Synonyms
  • Rochalimaea
  • Bacillary Angiomatosis (BA)
  • Cat Scratch Disease Antibody

Test Details

Methodology

Indirect fluorescent antibody (IFA)

Result Turnaround Time

1 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Test Includes

Bartonella henselae, IgG; Bartonella henselae, IgM; Bartonella quintana, IgG; Bartonella quintana, IgM

Use

Bartonella (formerly Rochalimaea) henselae has become firmly established as the primary etiologic agent for cat scratch disease (CSD). Bartonella quintana, known for some time as a cause of trench fever, is also associated with CSD and bacillary angiomatosis (BA). Both diseases frequently affect immunocompromised patients, particularly those infected with HIV-1. Although CSD is generally a self-limiting disease, it can be life-threatening.

Limitations

There is some cross-reactivity between the IgG classes of B. henselae and B. quintana.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.

References

Anderson BE, Neuman MA. Bartonella spp as emerging human pathogens. Clin Microbiol Rev. 1997 Apr; 10(2):203-219. 9105751
Chomel BB, Abbott RC, Kasten RW, et al. Bartonella henselae prevalence in domestic cats in California: Risk factors and association between bacteremia and antibody titers. J Clin Microbiol. 1995 Sep; 33(9):2445-2450. 7494043
Regnery RL, Anderson BE, Clarridge JE 3rd, Rodríguez-Barradas MC, Jones DC, Carr JH. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol. 1992 Feb; 30(2):265-274. 1371515
Regnery R, Tappero J. Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes. Emerg Infect Dis. 1995 Jan-Mar; 1(1):16-21. 8903149
Sander A, Posselt M, Oberle K, Bredt W. Seroprevalence of antibodies to Bartonella henselae in patients with cat scratch disease and in healthy controls: Evaluation and comparison of two commercial serological tests. Clin Diagn Lab Immunol. 1998 Jul; 5(4):486-490. 9665953
Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ. Rochalimaea sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol. 1992 Feb; 30(2):275-280. 1537892

Specimen Requirements

Specimen

Serum

Volume

2 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Storage Instructions

Room temperature

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
163162 Bartonella Antibody Panel 90251-0 163163 B. henselae IgG titer 6954-2
163162 Bartonella Antibody Panel 90251-0 163164 B. henselae IgM titer 6955-9
163162 Bartonella Antibody Panel 90251-0 163165 B. quintana IgG titer 44827-4
163162 Bartonella Antibody Panel 90251-0 163168 B. quintana IgM titer 44825-8
Order Code163162
Order Code NameBartonella Antibody Panel
Order Loinc90251-0
Result Code163163
Result Code NameB. henselae IgG
UofMtiter
Result LOINC6954-2
Order Code163162
Order Code NameBartonella Antibody Panel
Order Loinc90251-0
Result Code163164
Result Code NameB. henselae IgM
UofMtiter
Result LOINC6955-9
Order Code163162
Order Code NameBartonella Antibody Panel
Order Loinc90251-0
Result Code163165
Result Code NameB. quintana IgG
UofMtiter
Result LOINC44827-4
Order Code163162
Order Code NameBartonella Antibody Panel
Order Loinc90251-0
Result Code163168
Result Code NameB. quintana IgM
UofMtiter
Result LOINC44825-8