Test Details
Methodology
Immunofluorescence (IF)
Result Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
This test is recommended for differential evaluation of neuromuscular junction diseases including myasthenia gravis (MG).
Special Instructions
This assay currently is not available in New York state.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
References
Custom Additional Information
Autoantibodies directed against the contractile elements of striated muscle are found in 30% of adult patients with myasthenia gravis and 80% of those with thymoma. These antibodies may also be detected in patients with: Lambert-Eaton myasthenic syndrome, small-cell lung carcinoma, breast carcinoma, patients treated with D-penicillamine, bone marrow transplant recipients having graft-versus-host disease, and autoimmune liver disorders.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x3 |
Reference Range
Negative: <1:100
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Hemolyzed or lipemic serum
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 160184 | Striation Abs, Serum | 5372-8 | 161216 | Striation Abs, Serum | 5372-8 | |
| Order Code | 160184 | |||||
| Order Code Name | Striation Abs, Serum | |||||
| Order Loinc | 5372-8 | |||||
| Result Code | 161216 | |||||
| Result Code Name | Striation Abs, Serum | |||||
| UofM | ||||||
| Result LOINC | 5372-8 |