Skip to main content

PrEP Use Only: HCV Antibody With Reflex to Quantitative Real-time PCR

Test Number 144613
Test number copied
CPT 86803
Synonyms
  • HCV antibody with reflex
  • HIV PrEP
  • pre-exposure prophylaxis screening for HCV

Test Details

Methodology

Enzyme immunoassay (EIA) with reflex to real-time PCR

Result Turnaround Time

1 - 3 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Test Includes

Hepatitis C virus total antibody which, if positive, reflexes to quantitative HCV RNA.

Use

This test is used for HCV screening and diagnosis in patients administered HIV PrEP and diagnosis of active hepatitis C virus (HCV) infection.

Special Instructions

PrEP use only. Contains CPT code modifier for CARES Act.

If reflex test is performed, additional charges/CPT code(s) may apply.

Tests included within this profile may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for testing about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

Specimen Requirements

Specimen

Serum or plasma

Volume

3.0 mL

Minimum Volume

1.5 mL (Note: This volume does not allow for repeat testing.)

Container

Gel-barrier tube, plasma preparation tube (PPT), serum transfer tube, EDTA-plasma transfer tube

Collection Instructions

Centrifuge sample within 24 hours of collection. If tube other than a gel-barrier tube is used, or if sample will be shipped frozen, transfer separated serum/plasma to a screw-cap polypropylene transport tube. Ship refrigerated (preferred) or frozen.

Stability Requirements

Temperature

Period

Room temperature

24 hours

Refrigerated

6 days

Frozen

14 days

Storage Instructions

Refrigerated (preferred)

Causes for Rejection

Incorrect anticoagulant; PPT not centrifuged; frozen gel-barrier tube

References

American Association for the Study of Liver Diseases, Infectious Diseases Society of America. HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C: HCV Testing and Linkage to Care. HCVGuidelines.org website: https://www.hcvguidelines.org/evaluate/testing-and-linkage. Updated Aug 27, 2020. Accessed May 2021.
Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.34292926

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
144613 PrEP: HCV Ab RFX to Quant PCR 40726-2 144035 HCV Ab 40726-2
Order Code144613
Order Code NamePrEP: HCV Ab RFX to Quant PCR
Order Loinc40726-2
Result Code144035
Result Code NameHCV Ab
UofM
Result LOINC40726-2
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 144030 Interpretation: 144030 Interpretation: 13955-0
Reflex 1
Order Code144030
Order NameInterpretation:
Result Code144030
Result NameInterpretation:
UofM
Result LOINC13955-0
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550644 HCV RT-PCR, Quant (Non-Graph) 550338 Hepatitis C Quantitation IU/mL 11011-4
Reflex 1
Order Code550644
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550338
Result NameHepatitis C Quantitation
UofMIU/mL
Result LOINC11011-4
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550644 HCV RT-PCR, Quant (Non-Graph) 550338 Hepatitis C Quantitation IU/mL 11011-4
Reflex 1
Order Code550644
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550338
Result NameHepatitis C Quantitation
UofMIU/mL
Result LOINC11011-4
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550644 HCV RT-PCR, Quant (Non-Graph) 550339 HCV log10 log10 IU/mL 38180-6
Reflex 1
Order Code550644
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550339
Result NameHCV log10
UofMlog10 IU/mL
Result LOINC38180-6
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550644 HCV RT-PCR, Quant (Non-Graph) 550314 Test Information: 19147-8
Reflex 1
Order Code550644
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550314
Result NameTest Information:
UofM
Result LOINC19147-8
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550644 HCV RT-PCR, Quant (Non-Graph) 550396 Interpretation: 62365-2
Reflex 1
Order Code550644
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550396
Result NameInterpretation:
UofM
Result LOINC62365-2