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Sexually Transmitted Infections (STI) Profile

CPT 86592; 86704; 86706; 86803; 87340; 87389
Synonyms
  • HBV
  • HCV
  • Hepatitis
  • HIV
  • Syphilis

Test Details

Methodology

See individual test components.

Result Turnaround Time

1 - 4 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Test Includes

RPR with reflex to quantitative RPR and confirmatory Treponema pallidum antibodies; HIV p24 Antigen/Antibody with reflex to confirmation; HBV screening and diagnosis (HBsAg, anti-HBs, HBc-total with reflex to IgM); HCV antibody with reflex to quantitative real-time PCR. If reflex testing is performed, additional charges/CPT code(s) may apply.

Use

Screen for and diagnose sexually transmitted infections and blood borne pathogens including syphilis, hepatitis B virus (HBV), hepatitis C virus (HCV), and HIV. Testing aligns with current guidelines and recommendations.

Special Instructions

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

If reflex test is performed, additional charges/CPT code(s) may apply.

HIV p24 Antigen/Antibody With Reflex to Confirmation [083935] requires a dedicated, unopened, gel-barrier tube or red-top tube sent directly to the testing facility.

Limitations

Some of the assays in this panel have not been FDA cleared or approved for the screening of blood or plasma donors, nor have assay performance characteristics been established for immunocompromised or immunosuppressed patients, cord blood, or patients less than 2 years of age.

Specimen Requirements

Specimen

Serum

Volume

8 mL

Container

Gel-barrier tube

Collection Instructions

Usual blood collection technique

Stability Requirements

Test Number

Sample Type

Room Temperature

Refrigerated

Frozen

Freeze/thaw Cycles

144473

Serum or plasma

14 days

14 days

14 days

Stable x3

144050

Serum or plasma

Antibody test: 24 hours

PCR test: 24 hours

Antibody test: 6 days

PCR test: 72 hours

Antibody test: 14 days

PCR test: 6 weeks

N/A

N/A

012005

Serum

14 days

14 days

14 days

Stable x3

083935

Serum

48 hours

14 days

14 days

Stable x5

Storage Instructions

See individual test components.

Causes for Rejection

Gross hemolysis; gross lipemia; samples containing particulate matter or exhibiting obvious microbial contamination

References

AAP Committee on Fetus and Newborn and ACOG Committee on Obstetric Practice. Guidelines for Perinatal Care. Kilpatrick SJ, Papile LA, Macones GA, eds. 8th edition, September 2017.
Centers for Disease Control and Prevention (CDC). Hepatitis B. CDC website: www.cdc.gov/hepatitis/hbv/index.htm. Accessed March 2022.
Centers for Disease Control and Prevention (CDC), The American College of Obstetrics and Gynecologists. Screening and Referral Algorithm for Hepatitis B Virus (HBV) Infection Among Pregnant Women. CDC website: https://www.cdc.gov/hepatitis/hbv/pdfs/prenatalhbsagtesting_508.pdf. Accessed March 2022.
Schillie S, Vellozzi C, Reingold A, et al. Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2018; 67(1):1-31.29939980
U.S. Department of Health and Human Service. 2020. Sexually Transmitted Infections: National Strategic Plan for the United States 2021-2025. Washington, DC. Accessed March 2022 at https://www.hhs.gov/sites/default/files/STI-National-Strategic-Plan-2021-2025.pdf.
U.S. Preventive Services Task Force: Screening for Hepatitis B Virus Infection in Pregnant Women: Recommendation Statement. Am Fam Physician. 2020 Jan 15;101(2):112-114.31939639

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
144011 STI Profile 006510 HBsAg Screen 5196-1
144011 STI Profile 006408 Hep B Surface Ab, Qual 22322-2
144011 STI Profile 006718 Hep B Core Ab, Tot 13952-7
144011 STI Profile 006719 Rfx to HBc IgM 77202-0
144011 STI Profile 006720 Interpretation 56850-1
144011 STI Profile 144035 HCV Ab 40726-2
144011 STI Profile 006072 RPR 20507-0
144011 STI Profile 083936 HIV Ab/p24 Ag Screen 56888-1
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006510
Result Code NameHBsAg Screen
UofM
Result LOINC5196-1
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006408
Result Code NameHep B Surface Ab, Qual
UofM
Result LOINC22322-2
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006718
Result Code NameHep B Core Ab, Tot
UofM
Result LOINC13952-7
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006719
Result Code NameRfx to HBc IgM
UofM
Result LOINC77202-0
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006720
Result Code NameInterpretation
UofM
Result LOINC56850-1
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code144035
Result Code NameHCV Ab
UofM
Result LOINC40726-2
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code006072
Result Code NameRPR
UofM
Result LOINC20507-0
Order Code144011
Order Code NameSTI Profile
Order Loinc
Result Code083936
Result Code NameHIV Ab/p24 Ag Screen
UofM
Result LOINC56888-1
Reflex Table for HBsAg Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 016105 HBsAg Confirmation 016105 HBsAg Confirmation 7905-3
Reflex 1
Order Code016105
Order NameHBsAg Confirmation
Result Code016105
Result NameHBsAg Confirmation
UofM
Result LOINC7905-3
Reflex Table for Rfx to HBc IgM
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 016881 Hep B Core Ab, IgM 016881 Hep B Core Ab, IgM 24113-3
Reflex 1
Order Code016881
Order NameHep B Core Ab, IgM
Result Code016881
Result NameHep B Core Ab, IgM
UofM
Result LOINC24113-3
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 144030 Interpretation: 144030 Interpretation: 13955-0
Reflex 1
Order Code144030
Order NameInterpretation:
Result Code144030
Result NameInterpretation:
UofM
Result LOINC13955-0
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550362 HCV RT-PCR, Quant (Non-Graph) 550338 Hepatitis C Quantitation IU/mL 11011-4
Reflex 1
Order Code550362
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550338
Result NameHepatitis C Quantitation
UofMIU/mL
Result LOINC11011-4
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550362 HCV RT-PCR, Quant (Non-Graph) 550338 Hepatitis C Quantitation IU/mL 11011-4
Reflex 1
Order Code550362
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550338
Result NameHepatitis C Quantitation
UofMIU/mL
Result LOINC11011-4
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550362 HCV RT-PCR, Quant (Non-Graph) 550339 HCV log10 log10 IU/mL 38180-6
Reflex 1
Order Code550362
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550339
Result NameHCV log10
UofMlog10 IU/mL
Result LOINC38180-6
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550362 HCV RT-PCR, Quant (Non-Graph) 550314 Test Information: 19147-8
Reflex 1
Order Code550362
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550314
Result NameTest Information:
UofM
Result LOINC19147-8
Reflex Table for HCV Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 550362 HCV RT-PCR, Quant (Non-Graph) 550396 Interpretation: 62365-2
Reflex 1
Order Code550362
Order NameHCV RT-PCR, Quant (Non-Graph)
Result Code550396
Result NameInterpretation:
UofM
Result LOINC62365-2
Reflex Table for RPR
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 006464 RPR, Quant. 006464 RPR, Quant. titer 31147-2
Reflex 1
Order Code006464
Order NameRPR, Quant.
Result Code006464
Result NameRPR, Quant.
UofMtiter
Result LOINC31147-2
Reflex Table for RPR
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 012021 RPR Qn+TP Abs 006464 RPR, Quant. titer 31147-2
Reflex 1
Order Code012021
Order NameRPR Qn+TP Abs
Result Code006464
Result NameRPR, Quant.
UofMtiter
Result LOINC31147-2
Reflex Table for RPR
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 012021 RPR Qn+TP Abs 082371 Treponema pallidum Antibodies 47236-5
Reflex 1
Order Code012021
Order NameRPR Qn+TP Abs
Result Code082371
Result NameTreponema pallidum Antibodies
UofM
Result LOINC47236-5
Reflex Table for RPR
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 012021 RPR Qn+TP Abs 010002 Interpretation: 93479-4
Reflex 1
Order Code012021
Order NameRPR Qn+TP Abs
Result Code010002
Result NameInterpretation:
UofM
Result LOINC93479-4
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083941 HIV 1 Ab 68961-2
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083941
Result NameHIV 1 Ab
UofM
Result LOINC68961-2
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083942 HIV 2 Ab 81641-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083942
Result NameHIV 2 Ab
UofM
Result LOINC81641-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3
Reflex Table for HIV Ab/p24 Ag Screen
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 083940 HIV 1/2 Ab Differentiation 083954 Interpretation: 80203-3
Reflex 1
Order Code083940
Order NameHIV 1/2 Ab Differentiation
Result Code083954
Result NameInterpretation:
UofM
Result LOINC80203-3