Varicella Zoster Virus (VZV), Cerebrospinal Fluid (CSF), DNA PCR

CPT: 87798
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Expected Turnaround Time

2 - 4 days


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Specimen Requirements


Specimen

Cerebrospinal Fluid (CSF)


Volume

0.5 mL


Minimum Volume

0.2 mL


Container

Sterile container


Collection

To avoid delays in turnaround time when requesting multiple tests on frozen sample, please submit separate specimens for each test requested.


Storage Instructions

Frozen


Stability Requirements

Temperature

Period

Room temperature

Not acceptable (stability provided by manufacturer or literature reference)

Refrigerated

7 days (stability provided by manufacturer or literature reference)

Frozen

>7 days (stability provided by manufacturer or literature reference)


Causes for Rejection

Improperly labeled or unlabeled specimen; specimen that has grossly leaked in transit; specimen submitted in an improper collection/transport device; non-CSF specimens


Test Details


Use

This assay is used for the detection of Varicella Zoster Virus (VZV) DNA in cerebrospinal fluid.


Limitations

Results from this test must be considered in conjunction with the clinical history, epidemiological data and other laboratory information available to the clinician evaluating the patient.

Negative results do not rule out VZV infections of the CNS and should not be used as the sole basis for treatment or other patient management decisions.

False-negative results may occur if the viruses are present at a level that is below the analytical sensitivity of the assay or if the virus has genomic mutations, insertions, deletions or rearrangements, or if performed very early in the course of illness.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
139835 VZV PCR, CSF 21598-8 139836 VZV PCR, CSF 21598-8

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