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Minimum Inhibitory Concentration (MIC), One Drug

Test Number 096388
Test number copied
CPT 87186
Synonyms
  • Susceptibility Testing

Test Details

Methodology

Broth microdilution (MIC)

Result Turnaround Time

4 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

Test Includes

Susceptibility testing by minimum inhibitory concentration methodology. Identification is required to perform or provide an accurate interpretation for susceptibility testing; it will be done at an additional charge if not provided by the client.

Use

Determine minimum inhibitory concentration (MIC) susceptibility of a given organism to an antimicrobial agent

Special Instructions

Please list drug(s) to be tested.

Limitations

Determination of MIC on fastidious organisms may be attempted. If the organism of interest fails to grow, it will usually be reported out as unable to grow for MIC. A disc diffusion susceptibility test (Kirby-Bauer) susceptibility will be reported (susceptible, indeterminate, resistant) if possible.

Specimen Requirements

Specimen

Pure culture of bacteria to be tested

Volume

Viable colonies

Container

Agar slant in screw-cap container packed as an etiologic agent and a swab transport inoculated with the isolate from a pure culture. Maintain subculture at submitting laboratory.

Collection Instructions

Bacterium derived from cultured clinical sample. Send pure culture on maintenance media. Maintain subculture at submitting laboratory.

Reference Range

Minimal inhibitory concentration (MIC) reported. Results may be qualitatively reported as susceptible (S), intermediate (I), or resistant (R).

Storage Instructions

Maintain culture at room temperature.

Causes for Rejection

Inappropriate specimen transport device; unlabeled specimen or name discrepancy between specimen and request label; specimen received after prolonged delay (usually more than 72 hours)

References

Gill VJ, Witebsky FG, MacLowry JD. Multicategory interpretive reporting of susceptibility testing with selected antimicrobial concentrations. Ten years of laboratory and clinical experience. Clin Lab Med. 1989 Jun; 9(2):221-238. 2659242
Hindler JA, Thrupp LD. Interpretive guidelines for antimicrobial susceptibility test results: What do they mean? Clin Microbiol Newslet. 1989; 17:129-136.
National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing. Fourth Information Supplement. Villanova, Pa: NCCLS;1992. Document M100-S4.
Rosenblatt JE. Laboratory tests used to guide antimicrobial therapy. Mayo Clin Proc. 1991 Sep; 66(9):942-948. 1921504
Sherris JC. Antimicrobic susceptibility testing. A personal perspective. Clin Lab Med. 1989 Jun; 9(2):191-202. 2659240
Silver LL, Bostian KA. Discovery and development of new antibiotics: The problem of antibiotic resistance. Antimicrob Agents Chemother. 1993 Mar; 37(3):377-383. 8460908
Wilkowske CJ. General principles of antimicrobial therapy. Mayo Clin Proc. 1991 Sep; 66(9):931-941. 1681155

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096388 Min Inhibitory Conc (1 Drug) 21070-8 096388 Min Inhibitory Conc (1 Drug) 21070-8
Order Code096388
Order Code NameMin Inhibitory Conc (1 Drug)
Order Loinc21070-8
Result Code096388
Result Code NameMin Inhibitory Conc (1 Drug)
UofM
Result LOINC21070-8
Reflex Table for Min Inhibitory Conc (1 Drug)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080647 Result 080649 Result 1 43409-2
Reflex 1
Order Code080647
Order NameResult
Result Code080649
Result NameResult 1
UofM
Result LOINC43409-2
Reflex Table for Min Inhibitory Conc (1 Drug)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080647 Result 080650 Result 2 43409-2
Reflex 1
Order Code080647
Order NameResult
Result Code080650
Result NameResult 2
UofM
Result LOINC43409-2
Reflex Table for Min Inhibitory Conc (1 Drug)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080647 Result 080651 Result 3 43409-2
Reflex 1
Order Code080647
Order NameResult
Result Code080651
Result NameResult 3
UofM
Result LOINC43409-2
Reflex Table for Min Inhibitory Conc (1 Drug)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080647 Result 080652 Result 4 43409-2
Reflex 1
Order Code080647
Order NameResult
Result Code080652
Result NameResult 4
UofM
Result LOINC43409-2
Reflex Table for Min Inhibitory Conc (1 Drug)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080647 Result 080653 Antimicrobial Susceptibility 21070-8
Reflex 1
Order Code080647
Order NameResult
Result Code080653
Result NameAntimicrobial Susceptibility
UofM
Result LOINC21070-8