Test Details
Methodology
Immunonephelometry
Result Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Provides evidence of an existing or past streptococcal infection
Custom Additional Information
ADNase B antibodies react against the exoenzyme desoxyribonuclease B produced by streptococci. The detection of these antibodies provides evidence of an existing or past streptococcal infection (rheumatic fever, scarlet fever, tonsillitis, glomerulonephritis, and others). The antibody reaction against streptococcal DNase B starts later than the antibody production against streptolysin O, but it can then be detected on a greater percentage of patients.1 An increase in the antistreptolysin concentration rarely occurs with skin infections, while a rise in the ADNase B titer can be observed.1-3
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 9 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
• <1 year: not established
• 1 to 6 years: <78 U/mL
• 7 to 17 years: ≤170 U/mL
• 18 years and older: ≤120 U/mL
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Gross lipemia that cannot be clarified by ultracentrifugation; heat-inactivated samples; severe hemolysis
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 096289 | Anti-DNase B Strep Antibodies | 5133-4 | 123904 | Anti-DNase B Strep Antibodies | U/mL | 5133-4 |
| Order Code | 096289 | |||||
| Order Code Name | Anti-DNase B Strep Antibodies | |||||
| Order Loinc | 5133-4 | |||||
| Result Code | 123904 | |||||
| Result Code Name | Anti-DNase B Strep Antibodies | |||||
| UofM | U/mL | |||||
| Result LOINC | 5133-4 |