Epstein-Barr Virus (EBV) (Viral Capsid Antigen [VCA] and Early Antigen-Diffuse [EA(D)]), IgG Antibody Profile

TEST: 096255
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CPT: 86663; 86665
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Synonyms

  • EA(D)
  • EBV-EA
  • EBV-VCA
  • EBV-VCA/EA Antibodies, IgG

Test Includes

Epstein-Barr virus (EBV) early antigen antibody, IgG; Epstein-Barr virus (EBV) antibody to viral capsid antigen, IgG

Expected Turnaround Time

1 - 2 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Serum

Volume

2 mL

Container

Red-top tube or gel-barrier tube

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x4

Causes for Rejection

Hemolysis; lipemia; grossly icteric; visible particulate matter; gross bacterial contamination

Test Details

Use

Aid in the diagnosis of acute EBV (infectious mononucleosis) and EBV reactivation in conjunction with other serologic tests. The appearance of IgG antibodies to EA(D) is generally associated with the primary (acute) stage of EBV infection. For most individuals, EA(D) IgG antibodies are transient and are ogten undetectable after 6 months while VCA IgG antibodies persist indefinitely.

Limitations

The results for this test are not by themselves diagnostic and should be considered in association with other clinical data and patient symptoms.

This test is intended for qualitative determination only. The numeric value of the final result above the cutoff is not indicative of the amount of EBV-EA or EBV-VCA antibodies.

Methodology

Chemiluminescent immunoassay (CLIA)

Reference Interval

See individual tests.

Additional Information

Set up and reported Monday thru Friday.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096255 EBV VCA/EA Ab, IgG 096252 EBV Early Antigen Ab, IgG U/mL 50969-5
096255 EBV VCA/EA Ab, IgG 096235 EBV Ab VCA, IgG U/mL 5157-3

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf