Test Details
Methodology
Cell agglutination
Result Turnaround Time
3 - 8 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Titer
Use
Aid in the diagnosis of cryptococcosis
Limitations
Usefulness of test is limited to the ability of the host to make antibodies in response to the infection. Negative results do not rule out infection.
Custom Additional Information
Agglutination titers ≥1:2 are suggestive of infection with Cryptococcus neoformans. Agglutinins may be detected early in the course of the disease but if the disease progresses, excess antigen may be produced which renders antibodies undetectable. With effective chemotherapy, the antigen titer declines and antibody may once again be demonstrated. Antibodies may persist for long periods even after cessation of chemotherapy.
Specimen Requirements
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Gel-barrier tube or red-top tube
Reference Range
Negative: <1:2
Storage Instructions
Refrigerate. Specimen can be stored at 2°C to 8°C for 72 hours. Freeze for longer storage.
Causes for Rejection
Cerebrospinal fluid (CSF)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 082891 | Cryptococcus Antibodies, Quant | 6369-3 | 082891 | Cryptococcus Antibodies, Quant | 6369-3 | |
| Order Code | 082891 | |||||
| Order Code Name | Cryptococcus Antibodies, Quant | |||||
| Order Loinc | 6369-3 | |||||
| Result Code | 082891 | |||||
| Result Code Name | Cryptococcus Antibodies, Quant | |||||
| UofM | ||||||
| Result LOINC | 6369-3 |