Test Details
Methodology
Inductively coupled plasma/mass spectrometry (ICP/MS)
Result Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Aluminum, urine; creatinine, urine; aluminum:creatinine ratio; aluminum, urine (24-hour)
Use
Monitor patients for prior and ongoing exposure to aluminum. Patients at risk include:
• Infants on parenteral fluids, particularly parenteral nutrition
• Burn patients through administration of intravenous albumin, particularly with coexisting renal failure
• Adult and pediatric patients with chronic renal failure who accumulate aluminum readily from medications and dialysate
• Adult parenteral nutrition patients (less so, recently)
• Patients with industrial exposure
Monitor dialysate and water to prepare dialysate to prevent aluminum toxicity in dialysis patients.
Special Instructions
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Specimen Requirements
Specimen
Urine (random or 24-hour)
Volume
5 mL
Minimum Volume
1.5 mL
Container
Plastic urine container, no preservative
Collection Instructions
Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
• Environmental exposure: 5−30 μg/L, 0−32 μg/24 hours
• Aluminum:creatinine ratio: <50 μg/g creatinine
• Occupational exposure: 150 μg/g creatinine (collected at end of shift)1
Storage Instructions
Maintain specimen at room temperature.
Footnotes
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 071555 | Aluminum, Urine | 071557 | Aluminum, Urine | ug/L | 6929-4 | |
| 071555 | Aluminum, Urine | 723280 | Creatinine(Crt),U | g/L | 2161-8 | |
| 071555 | Aluminum, Urine | 071560 | Aluminum/Crt Ratio | ug/g creat | 13470-0 | |
| 071555 | Aluminum, Urine | 071559 | Aluminum,Urine 24 Hr | ug/24 hr | 26707-0 | |
| Order Code | 071555 | |||||
| Order Code Name | Aluminum, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071557 | |||||
| Result Code Name | Aluminum, Urine | |||||
| UofM | ug/L | |||||
| Result LOINC | 6929-4 | |||||
| Order Code | 071555 | |||||
| Order Code Name | Aluminum, Urine | |||||
| Order Loinc | ||||||
| Result Code | 723280 | |||||
| Result Code Name | Creatinine(Crt),U | |||||
| UofM | g/L | |||||
| Result LOINC | 2161-8 | |||||
| Order Code | 071555 | |||||
| Order Code Name | Aluminum, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071560 | |||||
| Result Code Name | Aluminum/Crt Ratio | |||||
| UofM | ug/g creat | |||||
| Result LOINC | 13470-0 | |||||
| Order Code | 071555 | |||||
| Order Code Name | Aluminum, Urine | |||||
| Order Loinc | ||||||
| Result Code | 071559 | |||||
| Result Code Name | Aluminum,Urine 24 Hr | |||||
| UofM | ug/24 hr | |||||
| Result LOINC | 26707-0 |