Test Details
Result Turnaround Time
Within 1 day
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Activated partial thromboplastin time (aPTT); international normalized ratio (INR); prothrombin time (PT)
Special Instructions
This aPTT test is for screening purposes only and is not intended for therapeutic monitoring. Please refer to Heparin Anti-Xa [117101] and thrombin inhibitors, etc for aPTT testing. If the patient's hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted. Refer Coagulation Collection Procedures for directions.
Footnotes
Custom Additional Information
See descriptions of individual tests.
Specimen Requirements
Specimen
Whole blood, plasma
Volume
4.5 mL, 2.7 mL, 1.8 mL
Minimum Volume
90% of full draw
Container
Blue-top (sodium citrate) tube; do not open tube unless plasma is to be frozen.
Collection Instructions
Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.1 Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.2,3 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples.4,5 When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Please print and use the Volume Guide for Coagulation Testing to ensure proper draw volume.
Reference Range
See table.
Age | Range |
|---|---|
Activated Partial Thromboplastin Time (aPTT) | |
0 to 3 d | Not established |
4 d to 6 m | 26−38 sec |
7 m to 17 y | 26−35 sec |
≥18 y | 24−33 sec |
Prothrombin Time (PT) | |
0 to 30 d | 9.8−13.2 sec |
1 to 6 m | 9.8−12.6 sec |
7 m to 1 y | 9.8−12.2 sec |
2 to 17 y | 9.9–12.1 sec |
≥18 y | 9.1−12.0 sec |
International Normalized Ratio (INR) | |
0 to 1 m | 0.9−1.4 |
>1 m | 0.9−1.2 |
Storage Instructions
Specimens are stable at room temperature for 24 hours. If testing cannot be completed within 24 hours, specimens should be centrifuged for at least 10 minutes at 1500xg. Plasma should then be transferred to a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze immediately and maintain frozen until tested. Refer to Coagulation Collection Procedures for directions.
Requirements for patients receiving heparin are different: If testing cannot be performed within one hour of collection, frozen plasma must be submitted. Specimens should be centrifuged for at least 15 minutes at 1500xg to produce platelet-poor plasma, and the plasma quick frozen and maintained in this condition until tested.
Patient Preparation
Draw specimen one hour before next dose of heparin if heparin is being given by intermittent injection. Do not draw from an arm with a heparin lock or heparinized catheter.
Causes for Rejection
Gross hemolysis; clotted specimen; frozen specimen thawed in transit; tubes <90% full; improper labeling; specimen collected in tube other than 3.2% citrate; refrigerated sample
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 020321 | PT and PTT | 34529-8 | 115107 | INR | 6301-6 | |
| 020321 | PT and PTT | 34529-8 | 015289 | Prothrombin Time | sec | 5902-2 |
| 020321 | PT and PTT | 34529-8 | 015116 | aPTT | sec | 14979-9 |
| Order Code | 020321 | |||||
| Order Code Name | PT and PTT | |||||
| Order Loinc | 34529-8 | |||||
| Result Code | 115107 | |||||
| Result Code Name | INR | |||||
| UofM | ||||||
| Result LOINC | 6301-6 | |||||
| Order Code | 020321 | |||||
| Order Code Name | PT and PTT | |||||
| Order Loinc | 34529-8 | |||||
| Result Code | 015289 | |||||
| Result Code Name | Prothrombin Time | |||||
| UofM | sec | |||||
| Result LOINC | 5902-2 | |||||
| Order Code | 020321 | |||||
| Order Code Name | PT and PTT | |||||
| Order Loinc | 34529-8 | |||||
| Result Code | 015116 | |||||
| Result Code Name | aPTT | |||||
| UofM | sec | |||||
| Result LOINC | 14979-9 |
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 115109 | INR (Thromborel-S) | 115109 | INR (Thromborel-S) | 6301-6 | |
| Reflex 1 | ||||||
| Order Code | 115109 | |||||
| Order Name | INR (Thromborel-S) | |||||
| Result Code | 115109 | |||||
| Result Name | INR (Thromborel-S) | |||||
| UofM | ||||||
| Result LOINC | 6301-6 | |||||
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
|---|---|---|---|---|---|---|
| Reflex 1 | 015290 | PT (Thromborel-S) | 015290 | PT (Thromborel-S) | sec | 5902-2 |
| Reflex 1 | ||||||
| Order Code | 015290 | |||||
| Order Name | PT (Thromborel-S) | |||||
| Result Code | 015290 | |||||
| Result Name | PT (Thromborel-S) | |||||
| UofM | sec | |||||
| Result LOINC | 5902-2 | |||||