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Expected Turnaround Time
4 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Whole blood
Volume
500 μL
Minimum Volume
100 μL
Container
Yellow-top ACD-B tube (acid citrate dextrose) or yellow-top ACD-A tube
Collection
Allow ACD tubes to fill completely; gently invert 8 to 10 times.
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 7 days |
Causes for Rejection
Blood collected in tubes other than ACD tubes; ACD collection tubes inadequately filled; hemolyzed specimens; clotted specimens
Test Details
Use
Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia.
Limitations
Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 007700 | Total Glutathione | 91685-8 | 007701 | Total Glutathione | ug/mL | 2383-8 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf