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Glutathione, Total

CPT 82978

Test Details

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Result Turnaround Time

4 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Use

Glutathione is a tripeptide and is the primary regulator of cellular redox states. Glutathione exists primarily in its reduced form (GSH), which upon oxidation forms the dimer, glutathione disulfide (GSSG). GSH can also form disulfide bridges with proteins as a result of oxidation or enzyme catalyzed reactions, giving rise to protein-bound glutathione (GSSP). Decreased glutathione levels in whole blood have been associated with Parkinson's disease, HIV, liver disease, renal failure, as well as preëclampsia.

Limitations

Results of this test are for investigational purposes only. The performance characteristics of this assay have been determined by LabCorp. The result should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.

Specimen Requirements

Specimen

Whole blood

Volume

500 μL

Minimum Volume

100 μL

Container

Yellow-top ACD-B tube (acid citrate dextrose) or yellow-top ACD-A tube

Collection Instructions

Allow ACD tubes to fill completely; gently invert 8 to 10 times.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

7 days

Storage Instructions

Room temperature

Causes for Rejection

Blood collected in tubes other than ACD tubes; ACD collection tubes inadequately filled; hemolyzed specimens; clotted specimens

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
007700 Total Glutathione 91685-8 007701 Total Glutathione ug/mL 2383-8
Order Code007700
Order Code NameTotal Glutathione
Order Loinc91685-8
Result Code007701
Result Code NameTotal Glutathione
UofMug/mL
Result LOINC2383-8