Test Details
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
3 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Lacosamide is a functional amino acid specifically synthesized as an anticonvulsant drug. In addition to being approved for use as adjunctive therapy in the treatment of partial-onset seizures, it is being investigated as a treatment for diabetic neuropathic pain.
Limitations
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
References
Specimen Requirements
Specimen
Serum or plasma
Volume
0.25 mL
Minimum Volume
0.10 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 105 days |
Freeze/thaw cycles | Stable x3 |
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Gel-barrier tube
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 007012 | Lacosamide | 59297-2 | 007016 | Lacosamide | ug/mL | 59297-2 |
| Order Code | 007012 | |||||
| Order Code Name | Lacosamide | |||||
| Order Loinc | 59297-2 | |||||
| Result Code | 007016 | |||||
| Result Code Name | Lacosamide | |||||
| UofM | ug/mL | |||||
| Result LOINC | 59297-2 |