Test Details
Methodology
Competitive chemilumescence immunoassay (CLIA)
Result Turnaround Time
1 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
The presence of antibody to hepatitis Be antigen (anti-HBe) can be used in conjunction with other serological and clinical information to determine the stage and prognosis of hepatitis B infection.
Custom Additional Information
The appearance of anti-HBe in patients who have previously been HBeAg positive indicates a reduced risk of infectivity. Failure of appearance implies disease activity and probable chronicity but patients with HBeAb may have chronic hepatitis. Chronic HBsAg carriers can be positive for either HBeAg or anti-HBe, but are less infectious when anti-HBe is present. HBe can persist for years, but usually disappears earlier than anti-HBs or anti-HBc. Anti-HBe has not been found as the sole serologic marker for hepatitis B infection.
Specimen Requirements
Specimen
Serum or plasma
Volume
0.5 mL
Minimum Volume
0.2 mL (Note: This volume does not allow for repeat testing.)
Container
Serum gel tube, serum transfer tube, red-top tube, lavender-top (EDTA) tube, plasma transfer tube
Collection Instructions
If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 7 days (stability provided by manufacturer or literature reference) |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
Negative
Storage Instructions
Room temperature
Causes for Rejection
Gross hemolysis or visible bacterial contamination
References
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 006635 | Hep Be Ab | 13953-5 | 006635 | Hep Be Ab | 13953-5 | |
| Order Code | 006635 | |||||
| Order Code Name | Hep Be Ab | |||||
| Order Loinc | 13953-5 | |||||
| Result Code | 006635 | |||||
| Result Code Name | Hep Be Ab | |||||
| UofM | ||||||
| Result LOINC | 13953-5 |