Test Details
Methodology
Latex immunoturbidimetry
Result Turnaround Time
Within 1 day
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
Quantitative concentration of CRP (mg/L) in serum
Use
CRP is an acute phase reactant, which can be used as a test for inflammatory diseases, infections, and neoplastic diseases. Progressive increases correlate with increases of inflammation/injury. CRP is a more sensitive, rapidly responding indicator than ESR. CRP may be used to detect early postoperative wound infection and to follow therapeutic response to anti-inflammatory agents. Recent reports have indicated that a highly sensitive version of the CRP assay may be used as an additional indicator for susceptibility to cardiac disease.
Limitations
CRP arises as a nonspecific response to tissue injury and inflammation.
Custom Additional Information
CRP is a pentameric globulin with mobility near the γ zone. It is an acute phase reactant which rises rapidly, but nonspecifically in response to tissue injury and inflammation. It is particularly useful in detecting occult infections, acute appendicitis, particularly in leukemia and in postoperative patients. In uncomplicated postoperative recovery, CRP peaks on the third postop day, and returns to preop levels by day seven. It may also be helpful in evaluating extension or reinfarction after myocardial infarction, and in following response to therapy in rheumatic disorders. It may help to differentiate Crohn's disease (high CRP) from ulcerative colitis (low CRP), and rheumatoid arthritis (high CRP) from uncomplicated lupus (low CRP).
Specimen Requirements
Specimen
Serum
Volume
1 mL
Container
Red-top tube or gel-barrier tube
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Reference Range
See table.
Age | Male (mg/L) | Female (mg/L) |
|---|---|---|
0 to 30 d | Not established | Not established |
1 m to 17 y | 0–7 | 0–9 |
>17 y | 0–10 | 0–10 |
Storage Instructions
Room temperature
Causes for Rejection
Gross hemolysis; lipemia
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 006627 | C-Reactive Protein, Quant | 1988-5 | 006627 | C-Reactive Protein, Quant | mg/L | 1988-5 |
| Order Code | 006627 | |||||
| Order Code Name | C-Reactive Protein, Quant | |||||
| Order Loinc | 1988-5 | |||||
| Result Code | 006627 | |||||
| Result Code Name | C-Reactive Protein, Quant | |||||
| UofM | mg/L | |||||
| Result LOINC | 1988-5 |